Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_0368Transposase IS4 family protein; COGs: COG3666 Transposase and inactivated derivatives; InterPro IPR002559; KEGG: tte:TTE2646 transposase; PFAM: transposase IS4 family protein; SPTR: Transposase; PFAM: Transposase DDE domain; Transposase domain (DUF772). (491 aa)    
Predicted Functional Partners:
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
       0.515
Toce_0369
COGs: COG4585 Signal transduction histidine kinase; InterProIPR005467:IPR016381:IPR003594:IPR008595:IPR 011712; KEGG: tte:TTE1682 sensory transduction histidine kinase; PFAM: Sensor DegS domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Sensor protein DegS; PFAM: Histidine kinase; Sensor protein DegS; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
       0.500
Toce_0370
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792:IPR001789; KEGG: cth:Cthe_1267 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
       0.500
Toce_0366
KEGG: nth:Nther_2344 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.472
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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