Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0369COGs: COG4585 Signal transduction histidine kinase; InterProIPR005467:IPR016381:IPR003594:IPR008595:IPR 011712; KEGG: tte:TTE1682 sensory transduction histidine kinase; PFAM: Sensor DegS domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Sensor protein DegS; PFAM: Histidine kinase; Sensor protein DegS; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (396 aa)    
Predicted Functional Partners:
Toce_0370
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792:IPR001789; KEGG: cth:Cthe_1267 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
 0.999
Toce_1545
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cac:CAC0174 response regulator; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.933
Toce_1159
MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: amt:Amet_2623 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: Protein-glutamate O-methyltransferase; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.
      0.858
Toce_0404
Sigma-70 region 4 type 2; InterPro IPR013249; KEGG: sli:Slin_3339 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70, region 4.
  
 
 0.579
Toce_0371
KEGG: pth:PTH_2758 hypothetical protein; SPTR: Hypothetical membrane protein.
       0.578
Toce_1029
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.526
Toce_1598
FlgN family protein; InterPro IPR007809; KEGG: cce:Ccel_0093 FlgN family protein; PFAM: FlgN family protein; SPTR: FlgN family protein; PFAM: FlgN protein.
  
     0.526
Toce_1126
Protein of unknown function DUF342; COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: cth:Cthe_0498 hypothetical protein; PFAM: protein of unknown function DUF342; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF342).
  
    0.519
Toce_1032
COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635:IPR002290:IPR005543:IPR017442:IPR 017441:IPR008271:IPR000719; KEGG: tpd:Teth39_1313 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Serine/threonine protein kinase with PASTA sensor(S); PFAM: Protein kinase domain; PASTA domain.
  
  
 0.502
Toce_0368
Transposase IS4 family protein; COGs: COG3666 Transposase and inactivated derivatives; InterPro IPR002559; KEGG: tte:TTE2646 transposase; PFAM: transposase IS4 family protein; SPTR: Transposase; PFAM: Transposase DDE domain; Transposase domain (DUF772).
       0.500
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.