STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Toce_0376COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mta:Moth_1777 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxopent-4-enoate hydratase. (257 aa)    
Predicted Functional Partners:
Toce_0378
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.996
Toce_0377
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
 0.989
Toce_0375
InterPro IPR001453; KEGG: mta:Moth_1778 molybdopterin binding domain-containing protein; PFAM: molybdopterin binding domain; SPTR: Molybdopterin binding domain; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
 
     0.863
Toce_0374
Quinolinate phosphoribosyl transferase; COGs: COG0157 Nicotinate-nucleotide pyrophosphorylase; InterPro IPR002638; KEGG: mta:Moth_1779 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; SPTR: Nicotinate-nucleotide pyrophosphorylase (Carboxylating); PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain.
       0.812
Toce_0379
BFD domain protein (2Fe-2S)-binding domain protein; COGs: COG4231 Indolepyruvate ferredoxin oxidoreductase alpha and beta subunits; InterPro IPR017896:IPR017900:IPR007419; KEGG: chy:CHY_1274 iron-sulfur cluster-binding protein; PFAM: BFD domain protein [2Fe-2S]-binding domain protein; SPTR: Iron-sulfur cluster-binding protein; PFAM: 4Fe-4S binding domain; BFD-like [2Fe-2S] binding domain.
 
     0.795
Toce_0380
KEGG: mta:Moth_1773 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.748
Toce_0381
Benzoate transporter; COGs: COG3135 Uncharacterized protein involved in benzoate metabolism; InterPro IPR003016:IPR004711; KEGG: mta:Moth_1772 benzoate transporter; PFAM: Benzoate membrane transport protein; SPTR: Benzoate transporter; TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; TIGRFAM: benzoate transporter.
 
     0.667
Toce_0382
Fe-S-cluster; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896:IPR017900; KEGG: pth:PTH_0486 Fe-S-cluster; SPTR: Fe-S-cluster; PFAM: 4Fe-4S binding domain.
       0.430
recD2
Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
       0.406
Toce_0383
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: chy:CHY_1712 aldehyde ferredoxin oxidoreductase, tungsten-containing; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Aldehyde ferredoxin oxidoreductase, tungsten-containing; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
       0.402
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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