| node1 | node2 | node1 annotation | node2 annotation | score |
| Toce_0376 | Toce_0377 | COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mta:Moth_1777 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxopent-4-enoate hydratase. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.989 |
| Toce_0376 | Toce_0378 | COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mta:Moth_1777 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxopent-4-enoate hydratase. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.996 |
| Toce_0377 | Toce_0376 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mta:Moth_1777 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxopent-4-enoate hydratase. | 0.989 |
| Toce_0377 | Toce_0378 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.999 |
| Toce_0377 | Toce_0555 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. | 0.900 |
| Toce_0377 | Toce_0830 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Phosphate butyryltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR012147:IPR002505; KEGG: nth:Nther_1682 phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate butyryltransferase; SPTR: Phosphate butyryltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate butyryltransferase. | 0.908 |
| Toce_0377 | Toce_0834 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR005476; KEGG: tpd:Teth39_0465 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Transketolase, C-terminal domain. | 0.900 |
| Toce_0377 | Toce_0835 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: adg:Adeg_1384 thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: Keto/oxoacid ferredoxin oxidoreductase, alpha subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.900 |
| Toce_0377 | Toce_1047 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR012147:IPR004614; KEGG: tte:TTE1482 phosphotransacetylase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase; SPTR: Phosphotransacetylase; TIGRFAM: phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase. | 0.908 |
| Toce_0377 | Toce_1203 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: aoe:Clos_1570 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: Thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.900 |
| Toce_0377 | Toce_1204 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR005476; KEGG: aoe:Clos_1571 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Transketolase, C-terminal domain. | 0.900 |
| Toce_0377 | Toce_1565 | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | Phosphate butyryltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR012147; KEGG: tte:TTE2204 phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate butyryltransferase; SPTR: Phosphotransacetylase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate butyryltransferase. | 0.908 |
| Toce_0378 | Toce_0376 | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | COGs: COG3971 2-keto-4-pentenoate hydratase; InterPro IPR002529; KEGG: mta:Moth_1777 4-oxalocrotonate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 2-oxopent-4-enoate hydratase; SPTR: 4-oxalocrotonate decarboxylase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: 2-oxopent-4-enoate hydratase. | 0.996 |
| Toce_0378 | Toce_0377 | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.999 |
| Toce_0555 | Toce_0377 | Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.900 |
| Toce_0555 | Toce_0834 | Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR005476; KEGG: tpd:Teth39_0465 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Transketolase, C-terminal domain. | 0.911 |
| Toce_0555 | Toce_0835 | Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. | Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: adg:Adeg_1384 thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: Keto/oxoacid ferredoxin oxidoreductase, alpha subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.909 |
| Toce_0555 | Toce_1047 | Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. | COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR012147:IPR004614; KEGG: tte:TTE1482 phosphotransacetylase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase; SPTR: Phosphotransacetylase; TIGRFAM: phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase. | 0.910 |
| Toce_0555 | Toce_1203 | Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. | 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: aoe:Clos_1570 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: Thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.909 |
| Toce_0555 | Toce_1204 | Propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR005476; KEGG: aoe:Clos_1571 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; SPTR: Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Transketolase, C-terminal domain. | 0.911 |