STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0382Fe-S-cluster; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896:IPR017900; KEGG: pth:PTH_0486 Fe-S-cluster; SPTR: Fe-S-cluster; PFAM: 4Fe-4S binding domain. (154 aa)    
Predicted Functional Partners:
Toce_0383
COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: chy:CHY_1712 aldehyde ferredoxin oxidoreductase, tungsten-containing; PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; PRIAM: Aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase; SPTR: Aldehyde ferredoxin oxidoreductase, tungsten-containing; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3.
 
 0.990
Toce_0243
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR013027:IPR006963:IPR006656:IPR 000759:IPR017900:IPR006655:IPR017896; KEGG: aoe:Clos_0277 molybdopterin oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: glutamate synt [...]
  
 
 0.986
Toce_2213
Nitrate reductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006655:IPR006963:IPR006656:IPR006657; KEGG: drm:Dred_1345 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; PRIAM: Nitrate reductase; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.986
Toce_0785
NAD-dependent formate dehydrogenase catalytic subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; Contains selenocysteine; InterProIPR006478:IPR006655:IPR006963:IPR006656:IPR 006657; KEGG: nth:Nther_0100 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase F [...]
 
 
 0.974
Toce_0813
COGs: COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit; InterPro IPR004461; KEGG: cdl:CDR20291_0655 putative carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; SPTR: Putative carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit.
    
 0.961
Toce_0799
Iron-sulfur cluster-binding protein CooF; COGs: COG1142 Fe-S-cluster-containing hydrogenase components 2; InterPro IPR017896:IPR017900; KEGG: chy:CHY_0086 iron-sulfur cluster-binding protein CooF; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
 
  
0.938
Toce_0335
Carbon-monoxide dehydrogenase, catalytic subunit; COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR010047:IPR004137; KEGG: dae:Dtox_2933 carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Carbon-monoxide dehydrogenase, catalytic subunit; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit.
    
 0.922
Toce_0761
Carbon-monoxide dehydrogenase, catalytic subunit; COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR010047:IPR004137; KEGG: dhd:Dhaf_1166 carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Carbon-monoxide dehydrogenase, catalytic subunit; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit.
    
 0.922
Toce_0800
Carbon-monoxide dehydrogenase, catalytic subunit; COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR010047:IPR004137; KEGG: amt:Amet_2016 carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; SPTR: Carbon-monoxide dehydrogenase, catalytic subunit; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit.
    
 0.922
Toce_2138
Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR000408:IPR011766; KEGG: ate:Athe_0877 thiamine pyrophosphate protein domain protein TPP-binding; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: Thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
   
 
 0.911
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.