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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Toce_0390Metal dependent phosphohydrolase; COGs: COG2316 hydrolase (HD superfamily); InterPro IPR006675:IPR006674; KEGG: chy:CHY_1871 HDIG domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: HDIG domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. (193 aa)    
Predicted Functional Partners:
lysS
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR002313:IPR004365:IPR004364:IPR018149:IPR 006195; KEGG: csc:Csac_0828 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family.
      0.906
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
 
     0.621
Toce_0387
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: cth:Cthe_0368 NCAIR mutase (PurE)-related protein; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: NCAIR mutase (PurE)-related protein; PFAM: AIR carboxylase.
       0.453
Toce_0391
Transcriptional regulator, GntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: tit:Thit_2160 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family.
       0.451
larC
Protein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
       0.449
Toce_0386
PP-loop domain protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR011063; KEGG: chy:CHY_1281 hypothetical protein; PFAM: PP-loop domain protein; SPTR: ExsB family protein; PFAM: NAD synthase; TIGRFAM: conserved hypothetical protein TIGR00268.
       0.433
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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