Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_0404Sigma-70 region 4 type 2; InterPro IPR013249; KEGG: sli:Slin_3339 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70 region 4 type 2; SPTR: RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: Sigma-70, region 4. (176 aa)    
Predicted Functional Partners:
Toce_0369
COGs: COG4585 Signal transduction histidine kinase; InterProIPR005467:IPR016381:IPR003594:IPR008595:IPR 011712; KEGG: tte:TTE1682 sensory transduction histidine kinase; PFAM: Sensor DegS domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Sensor protein DegS; PFAM: Histidine kinase; Sensor protein DegS; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.579
Toce_0403
Hypothetical protein.
       0.448
Toce_0372
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: tte:TTE2335 diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; GAF domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); TIGRFAM: diguanylate cyclase; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
 
 0.423
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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