Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_0431COGs: COG3451 Type IV secretory pathway VirB4 protein; KEGG: tpd:Teth39_0060 type IV secretory pathway VirB4 components-like protein; SPTR: Type IV secretory pathway VirB4 components-like protein; PFAM: Domain of unknown function DUF87; CagE, TrbE, VirB family, component of type IV transporter system. (594 aa)    
Predicted Functional Partners:
Toce_0430
KEGG: tpd:Teth39_0059 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.972
Toce_0426
TRAG family protein; COGs: COG3505 Type IV secretory pathway VirD4 protein; InterPro IPR003688; KEGG: tpd:Teth39_0052 TraG family protein; PFAM: TRAG family protein; SPTR: TRAG family protein; PFAM: TraG/TraD family.
 
  
 0.947
Toce_0425
KEGG: tpd:Teth39_0051 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.908
Toce_0432
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tpd:Teth39_0061 peptidase M23B; PFAM: Peptidase M23; SPTR: Peptidase M23; PFAM: Peptidase family M23.
 
     0.815
Toce_0428
KEGG: tpd:Teth39_0054 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.794
Toce_0429
KEGG: tpd:Teth39_0055 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
Toce_0421
Plasmid segregation actin-type ATPase ParM; KEGG: tpd:Teth39_0078 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.718
Toce_0433
KEGG: tpd:Teth39_0047 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.631
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.617
Toce_0427
KEGG: tpd:Teth39_0053 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.613
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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