STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0458KEGG: hypothetical protein; SPTR: Chaperone protein dnaJ. (39 aa)    
Predicted Functional Partners:
Toce_0459
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467:IPR003594:IPR004358; KEGG: cbe:Cbei_4175 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
       0.481
Toce_0460
Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789:IPR013972; KEGG: cbe:Cbei_4174 response regulator receiver; PFAM: YcbB domain protein; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; YcbB domain.
       0.481
Toce_0457
COGs: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB; InterPro IPR010327; KEGG: tpd:Teth39_0844 2-hydroxyglutaryl-CoA dehydratase, D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; SPTR: 2-hydroxyglutaryl-CoA dehydratase D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.
       0.452
Toce_0456
CoA-substrate-specific enzyme activase; COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR008275:IPR010327:IPR002731; KEGG: tte:TTE1113 2-hydroxyglutaryl-CoA dehydratase activator; PFAM: ATPase BadF/BadG/BcrA/BcrD type; 2-hydroxyglutaryl-CoA dehydratase D-component; PRIAM: Benzoyl-CoA reductase; SPTR: CoA-substrate-specific enzyme activase; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; TIGRFAM: CoA-substrate-specific enzyme activase, putative.
       0.414
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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