| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0002 | Toce_0253 | Toce_0002 | Toce_0253 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: tpd:Teth39_0572 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family. | 0.450 |
| Toce_0002 | Toce_0454 | Toce_0002 | Toce_0454 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | AAA family ATPase, CDC48 subfamily; COGs: COG0464 ATPase of the AAA+ class; InterProIPR003960:IPR005938:IPR003593:IPR003338:IPR 004201:IPR003959; KEGG: mta:Moth_1594 AAA family ATPase, CDC48 subfamily protein; PFAM: AAA ATPase central domain protein; AAA ATPase VAT domain protein; cell division protein 48 CDC48 domain 2; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: AAA family ATPase, CDC48 subfamily; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: Cell division protein 48 (CDC48), N-terminal domain; ATPase family associated with various cellular activities (AAA); Cell di [...] | 0.804 |
| Toce_0002 | Toce_1185 | Toce_0002 | Toce_1185 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | 0.804 |
| Toce_0002 | Toce_1679 | Toce_0002 | Toce_1679 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | D-proline reductase (dithiol); KEGG: cbf:CLI_3802 glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PRIAM: D-proline reductase (dithiol); SPTR: Glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PFAM: Glycine/sarcosine/betaine reductase component B subunits. | 0.977 |
| Toce_0002 | dinB | Toce_0002 | Toce_0463 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.975 |
| Toce_0002 | polA | Toce_0002 | Toce_1653 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.992 |
| Toce_0002 | recA | Toce_0002 | Toce_1215 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.941 |
| Toce_0002 | topA | Toce_0002 | Toce_1085 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.922 |
| Toce_0253 | Toce_0002 | Toce_0253 | Toce_0002 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: tpd:Teth39_0572 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.450 |
| Toce_0253 | dinB | Toce_0253 | Toce_0463 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: tpd:Teth39_0572 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family. | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.743 |
| Toce_0253 | polA | Toce_0253 | Toce_1653 | Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: tpd:Teth39_0572 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.439 |
| Toce_0454 | Toce_0002 | Toce_0454 | Toce_0002 | AAA family ATPase, CDC48 subfamily; COGs: COG0464 ATPase of the AAA+ class; InterProIPR003960:IPR005938:IPR003593:IPR003338:IPR 004201:IPR003959; KEGG: mta:Moth_1594 AAA family ATPase, CDC48 subfamily protein; PFAM: AAA ATPase central domain protein; AAA ATPase VAT domain protein; cell division protein 48 CDC48 domain 2; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: AAA family ATPase, CDC48 subfamily; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: Cell division protein 48 (CDC48), N-terminal domain; ATPase family associated with various cellular activities (AAA); Cell di [...] | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.804 |
| Toce_0454 | Toce_1679 | Toce_0454 | Toce_1679 | AAA family ATPase, CDC48 subfamily; COGs: COG0464 ATPase of the AAA+ class; InterProIPR003960:IPR005938:IPR003593:IPR003338:IPR 004201:IPR003959; KEGG: mta:Moth_1594 AAA family ATPase, CDC48 subfamily protein; PFAM: AAA ATPase central domain protein; AAA ATPase VAT domain protein; cell division protein 48 CDC48 domain 2; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: AAA family ATPase, CDC48 subfamily; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: Cell division protein 48 (CDC48), N-terminal domain; ATPase family associated with various cellular activities (AAA); Cell di [...] | D-proline reductase (dithiol); KEGG: cbf:CLI_3802 glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PRIAM: D-proline reductase (dithiol); SPTR: Glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PFAM: Glycine/sarcosine/betaine reductase component B subunits. | 0.785 |
| Toce_0454 | dinB | Toce_0454 | Toce_0463 | AAA family ATPase, CDC48 subfamily; COGs: COG0464 ATPase of the AAA+ class; InterProIPR003960:IPR005938:IPR003593:IPR003338:IPR 004201:IPR003959; KEGG: mta:Moth_1594 AAA family ATPase, CDC48 subfamily protein; PFAM: AAA ATPase central domain protein; AAA ATPase VAT domain protein; cell division protein 48 CDC48 domain 2; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: AAA family ATPase, CDC48 subfamily; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: Cell division protein 48 (CDC48), N-terminal domain; ATPase family associated with various cellular activities (AAA); Cell di [...] | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.778 |
| Toce_1185 | Toce_0002 | Toce_1185 | Toce_0002 | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.804 |
| Toce_1185 | Toce_1679 | Toce_1185 | Toce_1679 | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | D-proline reductase (dithiol); KEGG: cbf:CLI_3802 glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PRIAM: D-proline reductase (dithiol); SPTR: Glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PFAM: Glycine/sarcosine/betaine reductase component B subunits. | 0.785 |
| Toce_1185 | dinB | Toce_1185 | Toce_0463 | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.778 |
| Toce_1679 | Toce_0002 | Toce_1679 | Toce_0002 | D-proline reductase (dithiol); KEGG: cbf:CLI_3802 glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PRIAM: D-proline reductase (dithiol); SPTR: Glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PFAM: Glycine/sarcosine/betaine reductase component B subunits. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.977 |
| Toce_1679 | Toce_0454 | Toce_1679 | Toce_0454 | D-proline reductase (dithiol); KEGG: cbf:CLI_3802 glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PRIAM: D-proline reductase (dithiol); SPTR: Glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PFAM: Glycine/sarcosine/betaine reductase component B subunits. | AAA family ATPase, CDC48 subfamily; COGs: COG0464 ATPase of the AAA+ class; InterProIPR003960:IPR005938:IPR003593:IPR003338:IPR 004201:IPR003959; KEGG: mta:Moth_1594 AAA family ATPase, CDC48 subfamily protein; PFAM: AAA ATPase central domain protein; AAA ATPase VAT domain protein; cell division protein 48 CDC48 domain 2; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: AAA family ATPase, CDC48 subfamily; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: Cell division protein 48 (CDC48), N-terminal domain; ATPase family associated with various cellular activities (AAA); Cell di [...] | 0.785 |
| Toce_1679 | Toce_1185 | Toce_1679 | Toce_1185 | D-proline reductase (dithiol); KEGG: cbf:CLI_3802 glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PRIAM: D-proline reductase (dithiol); SPTR: Glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PFAM: Glycine/sarcosine/betaine reductase component B subunits. | Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K. | 0.785 |
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