Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Toce_0485Peptidase S8 and S53 subtilisin kexin sedolisin; COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209; KEGG: mta:Moth_2027 aerolysin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: Aerolysin. Serine peptidase. MEROPS family S08A; PFAM: Subtilase family; Belongs to the peptidase S8 family. (386 aa)    
Predicted Functional Partners:
Toce_0486
KEGG: mta:Moth_2028 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.776
Toce_0496
S-layer domain protein; InterPro IPR001119; KEGG: gym:GYMC10_1663 S-layer domain protein; PFAM: S-layer domain protein; SPTR: S-layer associated multidomain endoglucanase; PFAM: S-layer homology domain.
 
 
 0.767
Toce_0497
S-layer domain protein; InterPro IPR001119; KEGG: tex:Teth514_1781 alpha amylase, catalytic region; PFAM: S-layer domain protein; SPTR: Alpha amylase, catalytic region; PFAM: S-layer homology domain.
 
 
 0.548
Toce_0484
Hypothetical protein; KEGG: gla:GL50803_8610 Coiled-coil protein; SPTR: Putative uncharacterized protein.
       0.543
Toce_0989
Hypothetical protein; KEGG: swo:Swol_1076 Ig-like domain-containing protein; SPTR: Surface proteins containing Ig-like domains-like; PFAM: The GLUG motif.
 
 
 0.493
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.484
Toce_1032
COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635:IPR002290:IPR005543:IPR017442:IPR 017441:IPR008271:IPR000719; KEGG: tpd:Teth39_1313 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Serine/threonine protein kinase with PASTA sensor(S); PFAM: Protein kinase domain; PASTA domain.
   
 
 0.457
Toce_0881
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR001757:IPR018303:IPR006069:IPR004014:IPR 008250:IPR005834:IPR006068; KEGG: cpo:COPRO5265_1364 cation-transporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Cation-transporting ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehaloge [...]
   
 
 0.439
Toce_1342
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR001757:IPR004014:IPR008250:IPR005834:IPR 006068:IPR018303:IPR000695; KEGG: tpd:Teth39_0231 calcium-translocating P-type ATPase, PMCA-type; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Calcium-translocating P-type ATPase, PMCA-type; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ [...]
   
 
 0.439
Toce_1223
DNA translocase FtsK; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR002543:IPR018541; KEGG: pth:PTH_1293 DNA segregation ATPase FtsK/SpoIIIE and related proteins; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: DNA segregation ATPase FtsK/SpoIIIE and related proteins; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family.
  
 
 0.437
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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