Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_0515Glycerol 2-dehydrogenase (NAD+); COGs: COG0371 Glycerol dehydrogenase; InterProIPR006162:IPR018211:IPR016160:IPR016205:IPR 001670; KEGG: cno:NT01CX_0287 glycerol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase. (387 aa)    
Predicted Functional Partners:
Toce_0549
COGs: COG4909 Propanediol dehydratase large subunit; InterPro IPR003206; KEGG: tex:Teth514_1953 glycerol dehydratase; PFAM: dehydratase large subunit; PRIAM: Glycerol dehydratase; SPTR: Glycerol dehydratase; PFAM: Dehydratase large subunit.
    
 0.914
Toce_0550
Dehydratase medium subunit; InterPro IPR003208; KEGG: tex:Teth514_1952 dehydratase, medium subunit; PFAM: dehydratase medium subunit; SPTR: Dehydratase, medium subunit; PFAM: Dehydratase medium subunit.
    
 0.911
Toce_0551
COGs: COG4910 Propanediol dehydratase small subunit; InterPro IPR003207; KEGG: tex:Teth514_1951 dehydratase, small subunit; PFAM: dehydratase small subunit; SPTR: Dehydratase, small subunit; PFAM: Dehydratase small subunit.
    
  0.904
Toce_1737
COGs: COG0388 amidohydrolase; InterPro IPR003010:IPR001110; KEGG: gym:GYMC10_2272 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase.
      0.544
Toce_0871
COGs: COG0469 Pyruvate kinase; InterProIPR001697:IPR018209:IPR015793:IPR015794:IPR 008279; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
      
 0.505
Toce_0365
Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR000169:IPR001303; KEGG: drm:Dred_2062 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; SPTR: Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase.
  
  
 0.481
Toce_0559
ATP/cobalamin adenosyltransferase; COGs: COG2096 conserved hypothetical protein; InterPro IPR017858:IPR009221:IPR002779:IPR005624; KEGG: tex:Teth514_1943 ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; protein of unknown function DUF336; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: ATP--cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: Domain of unknown function (DUF336); Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase.
     
 0.428
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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