Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_0520Transcriptional modulator of MazE/toxin, MazF; COGs: COG2337 Growth inhibitor; InterPro IPR003477; KEGG: gka:GK1648 ppGpp-regulated growth inhibitor (ChpA/MazF); PFAM: PemK family protein; SPTR: PpGpp-regulated growth inhibitor (ChpA/MazF); manually curated; PFAM: PemK-like protein. (109 aa)    
Predicted Functional Partners:
Toce_0521
Transcriptional regulator/antitoxin, MazE; COGs: COG2336 Growth regulator; InterPro IPR007159; KEGG: gyc:GYMC61_2489 transcriptional regulator/antitoxin, MazE; PFAM: SpoVT/AbrB domain protein; SPTR: Suppressor of ppGpp-regulated growth inhibitor (ChpA/MazF); PFAM: SpoVT / AbrB like domain.
 
 
 0.993
Toce_1914
KEGG: aoe:Clos_2274 CopG family transcriptional regulator; SPTR: Putative transcriptional regulator, CopG family.
  
 
 0.861
Toce_1961
COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: cbe:Cbei_3315 HxlR family transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: Transcriptional regulator, HxlR family; PFAM: HxlR-like helix-turn-helix.
   
    0.535
Toce_0523
DNA polymerase beta domain protein region; InterPro IPR002934; KEGG: dth:DICTH_0448 nucleotidyltransferase domain, putative; PFAM: DNA polymerase beta domain protein region; SPTR: Nucleotidyltransferase domain, putative; PFAM: Nucleotidyltransferase domain.
       0.487
Toce_0522
HEPN domain protein; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: dth:DICTH_0449 HEPN domain, putative; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: Hepn domain, putative; PFAM: HEPN domain.
       0.485
Toce_0438
Protein of unknown function UPF0150; InterPro IPR005357; KEGG: pth:PTH_2782 hypothetical protein; PFAM: protein of unknown function UPF0150; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0150).
  
   
 0.434
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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