Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Toce_0526CRISPR-associated protein, Csm3 family; COGs: COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR013412:IPR005537; KEGG: csc:Csac_0077 CRISPR-associated RAMP Csm3 family protein; PFAM: protein of unknown function DUF324; SPTR: CRISPR-associated RAMP protein, Csm3 family; TIGRFAM: CRISPR-associated RAMP protein, Csm3 family; PFAM: RAMP superfamily; TIGRFAM: CRISPR-associated RAMP protein, Csm3 family. (272 aa)    
Predicted Functional Partners:
Toce_0527
CRISPR-associated RAMP protein, Csm4 family; COGs: COG1567 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005510:IPR005537; KEGG: tme:Tmel_1673 CRISPR-associated RAMP Csm4 family protein; PFAM: protein of unknown function DUF324; SPTR: CRISPR-associated RAMP protein, Csm4 family; TIGRFAM: CRISPR-associated RAMP protein, Csm4 family; PFAM: RAMP superfamily; TIGRFAM: CRISPR-associated RAMP protein, Csm4 family.
 
 
 0.998
Toce_0525
InterPro IPR010149; KEGG: csc:Csac_0076 CRISPR-associated Csm2 family protein; PFAM: CRISPR-associated protein TM1810 domain protein; SPTR: CRISPR-associated protein, Csm2 family; TIGRFAM: CRISPR-associated protein, Csm2 family; PFAM: Protein of unknown function (DUF310); TIGRFAM: CRISPR-associated protein, Csm2 family.
 
 
 0.997
Toce_0528
CRISPR-associated RAMP protein, Csm5 family; COGs: COG1332 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR010173:IPR005537; KEGG: ate:Athe_2700 CRISPR-associated RAMP protein, Csm5 family; PFAM: protein of unknown function DUF324; SPTR: CRISPR-associated RAMP protein, Csm5 family; TIGRFAM: CRISPR-associated RAMP protein, Csm5 family; PFAM: RAMP superfamily; TIGRFAM: CRISPR-associated RAMP protein, Csm5 family.
 
 
 0.997
Toce_0524
CRISPR-associated protein, Csm1 family; COGs: COG1353 hydrolase of the HD superfamily (permuted catalytic motifs); InterPro IPR000160:IPR013408; KEGG: ate:Athe_2704 metal dependent phosphohydrolase; SPTR: Metal dependent phosphohydrolase; TIGRFAM: CRISPR-associated protein, Csm1 family; PFAM: HD domain; TIGRFAM: CRISPR-associated protein, Csm1 family.
 
 
 0.993
Toce_0529
CRISPR-associated protein Cas6; COGs: COG1583 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR010156:IPR002743; KEGG: chy:CHY_2139 CRISPR-associated Cas family protein; PFAM: protein of unknown function DUF57; SPTR: CRISPR-associated protein Cas6; TIGRFAM: CRISPR-associated protein Cas6; PFAM: CRISPR associated protein Cas6; TIGRFAM: CRISPR-associated protein Cas6.
     
 0.766
Toce_0530
InterPro IPR010171:IPR019016; KEGG: ate:Athe_2714 CRISPR-associated protein, MJ1666 family; PFAM: CRISPR-associated protein DxTHG; SPTR: CRISPR-associated protein, MJ1666 family; TIGRFAM: CRISPR-associated protein, MJ1666 family; PFAM: CRISPR-associated (Cas) DxTHG family; TIGRFAM: CRISPR-associated protein, MJ1666 family.
       0.765
Toce_0531
InterPro IPR013409; KEGG: dtu:Dtur_0613 CRISPR-associated protein, Csx3 family; PFAM: CRISPR-associated protein Csx3; SPTR: CRISPR-associated protein, Csx3 family; TIGRFAM: CRISPR-associated protein, Csx3 family; PFAM: CRISPR-associated protein (Cas_csx3); TIGRFAM: CRISPR-associated protein, Csx3 family.
       0.621
cas2
CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.489
Toce_0457
COGs: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB; InterPro IPR010327; KEGG: tpd:Teth39_0844 2-hydroxyglutaryl-CoA dehydratase, D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; SPTR: 2-hydroxyglutaryl-CoA dehydratase D-component; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.
  
     0.472
cas1
CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
     0.431
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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