STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Experiments
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[Homology]
Score
Toce_0543HEPN domain protein; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: tye:THEYE_A1691 HEPN domain, putative; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: Hepn domain, putative; PFAM: HEPN domain. (128 aa)    
Predicted Functional Partners:
Toce_0542
InterPro IPR002934; KEGG: pai:PAE0273 hypothetical protein; PFAM: DNA polymerase beta domain protein region; SPTR: Putative uncharacterized protein; PFAM: Nucleotidyltransferase domain.
 
     0.948
Toce_2162
Protein of unknown function DUF86; COGs: COG2445 conserved hypothetical protein; InterPro IPR008201; KEGG: ate:Athe_0224 protein of unknown function DUF86; PFAM: protein of unknown function DUF86; SPTR: Putative toxin-antitoxin system, antitoxin component; PFAM: Protein of unknown function DUF86.
  
     0.707
Toce_0213
DNA polymerase beta domain protein region; InterPro IPR002934; KEGG: chy:CHY_1716 nucleotidyltransferase/HEPN domain-containing protein; PFAM: DNA polymerase beta domain protein region; SPTR: Nucleotidyltransferase/HEPN domain protein; PFAM: Nucleotidyltransferase domain.
 
 
   0.633
Toce_1939
Protein of unknown function DUF86; COGs: COG2445 conserved hypothetical protein; InterPro IPR008201; KEGG: ckr:CKR_1141 hypothetical protein; PFAM: protein of unknown function DUF86; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF86.
  
     0.593
Toce_0522
HEPN domain protein; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: dth:DICTH_0449 HEPN domain, putative; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: Hepn domain, putative; PFAM: HEPN domain.
  
     0.575
Toce_0544
Copper amine oxidase domain protein; COGs: COG3858 glycosyl hydrolase; InterPro IPR012854:IPR001223; KEGG: tit:Thit_2291 copper amine oxidase domain protein; PFAM: copper amine oxidase domain protein; glycoside hydrolase family 18; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain; Glycosyl hydrolases family 18.
       0.541
Toce_1938
DNA polymerase beta domain protein region; InterPro IPR002934; KEGG: chy:CHY_1896 nucleotidyltransferase domain-containing protein; PFAM: DNA polymerase beta domain protein region; SPTR: Nucleotidyltransferase domain protein; PFAM: Nucleotidyltransferase domain.
 
     0.519
Toce_0453
COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR017896:IPR017900:IPR011898:IPR019752; KEGG: mta:Moth_1593 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidored [...]
  
     0.507
Toce_0541
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterProIPR001034:IPR002178:IPR013011:IPR011608:IPR 007737; KEGG: tit:Thit_0523 PTS modulated transcriptional regulator, MtlR family; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS modulated transcriptional regulator, MtlR family; PFAM: Mga helix-turn-helix domain; HTH domain; PRD domain; PTS system, Lactose/Cellobiose specific IIB subunit; Phosph [...]
       0.487
Toce_0682
InterPro IPR002934; KEGG: rrs:RoseRS_4091 DNA polymerase beta subunit; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase, beta domain protein region; PFAM: Nucleotidyltransferase domain.
 
     0.463
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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