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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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Toce_0545Histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003594:IPR018771:IPR010559:IPR004358; KEGG: tex:Teth514_1959 histidine kinase; PFAM: Transcription regulator,histidine kinase sensor-like; histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Predicted histidine kinase sensor domain. (408 aa)    
Predicted Functional Partners:
Toce_0546
Two component transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterProIPR018060:IPR001789:IPR018062:IPR000005:IPR 020449; KEGG: tex:Teth514_1958 response regulator receiver protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family.
 
  
 0.961
Toce_0208
Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: adg:Adeg_0898 two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; SPTR: Transcriptional regulator, LytR/AlgR family; PFAM: Response regulator receiver domain; LytTr DNA-binding domain.
 
  
 0.890
Toce_1871
Periplasmic binding protein/LacI transcriptional regulator; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: tte:TTE0765 periplasmic sugar-binding proteins; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic sugar-binding proteins; PFAM: family.
  
 
 0.817
Toce_0559
ATP/cobalamin adenosyltransferase; COGs: COG2096 conserved hypothetical protein; InterPro IPR017858:IPR009221:IPR002779:IPR005624; KEGG: tex:Teth514_1943 ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; protein of unknown function DUF336; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: ATP--cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: Domain of unknown function (DUF336); Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase.
 
   
 0.772
Toce_0548
COGs: COG4816 Ethanolamine utilization protein; InterPro IPR009193:IPR000249; KEGG: tex:Teth514_1954 microcompartments protein; PFAM: microcompartments protein; SPTR: Microcompartments protein; PFAM: BMC domain.
 
  
 0.738
Toce_2004
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: swo:Swol_1680 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
   
 0.720
Toce_1742
Two component transcriptional regulator, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterProIPR001789:IPR000005:IPR020449:IPR018060:IPR 018062; KEGG: tit:Thit_0428 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix pro [...]
  
 0.711
Toce_0549
COGs: COG4909 Propanediol dehydratase large subunit; InterPro IPR003206; KEGG: tex:Teth514_1953 glycerol dehydratase; PFAM: dehydratase large subunit; PRIAM: Glycerol dehydratase; SPTR: Glycerol dehydratase; PFAM: Dehydratase large subunit.
 
   
 0.688
Toce_0553
KEGG: tex:Teth514_1949 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Dehydratase medium subunit.
 
     0.681
Toce_0550
Dehydratase medium subunit; InterPro IPR003208; KEGG: tex:Teth514_1952 dehydratase, medium subunit; PFAM: dehydratase medium subunit; SPTR: Dehydratase, medium subunit; PFAM: Dehydratase medium subunit.
 
   
 0.659
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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