Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Toce_0578Cupin 2 conserved barrel domain protein; COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR013096; KEGG: ctc:CTC00439 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Conserved protein; PFAM: Cupin domain. (115 aa)    
Predicted Functional Partners:
Toce_0577
Putative PAS/PAC sensor protein; COGs: COG2461 conserved hypothetical protein; InterPro IPR000014:IPR007380:IPR012312:IPR013656; KEGG: mta:Moth_1931 hypothetical protein; PFAM: protein of unknown function DUF438; Hemerythrin HHE cation binding domain protein; PAS fold-4 domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: PAS sensor protein; PFAM: Family of unknown function (DUF438); Hemerythrin HHE cation binding domain; PAS fold; TIGRFAM: PAS domain S-box.
 
   
 0.722
Toce_0579
Protein of unknown function DUF820; COGs: COG4636 conserved hypothetical protein; InterPro IPR008538; KEGG: ate:Athe_0024 protein of unknown function DUF820; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820).
       0.543
Toce_0591
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: csc:Csac_2320 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
  
  
 0.539
Toce_0580
Ferripyochelin binding protein (fbp); COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: nth:Nther_0108 ferripyochelin binding protein (fbp); SPTR: Ferripyochelin binding protein (Fbp).
       0.480
Toce_0325
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
  
  
 0.470
Toce_0794
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: dsy:DSY2716 hypothetical protein; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
  
  
 0.470
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.429
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
  
  
 0.403
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
    0.401
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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