STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0587Nucleoside-binding protein; COGs: COG1744 Uncharacterized ABC-type transport system periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: chy:CHY_1536 basic membrane protein family protein; PFAM: basic membrane lipoprotein; SPTR: Basic membrane protein family protein; PFAM: Basic membrane protein. (367 aa)    
Predicted Functional Partners:
Toce_0588
Nucleoside ABC transporter ATP-binding protein; COGs: COG3845 ABC-type uncharacterized transport systems ATPase components; InterPro IPR003439:IPR017871:IPR003593; KEGG: chy:CHY_1535 putative sugar ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative sugar ABC transporter, ATP-binding protein; PFAM: ABC transporter.
 
 0.997
Toce_0590
Nucleoside ABC transporter membrane protein; COGs: COG1079 ABC-type transport system permease component; InterPro IPR001851; KEGG: chy:CHY_1533 putative sugar ABC transporter, permease protein; PFAM: inner-membrane translocator; SPTR: Putative sugar ABC transporter, permease protein; PFAM: Branched-chain amino acid transport system / permease component.
 
 
 0.994
Toce_0589
Inner-membrane translocator; COGs: COG4603 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: chy:CHY_1534 putative sugar ABC transporter, permease protein; PFAM: inner-membrane translocator; SPTR: Putative sugar ABC transporter, permease protein; PFAM: Branched-chain amino acid transport system / permease component.
 
 
 0.991
Toce_0593
COGs: COG0213 Thymidine phosphorylase; InterProIPR017872:IPR018090:IPR000053:IPR017459:IPR 000312:IPR013102; KEGG: csc:Csac_2318 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; SPTR: Thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase.
     
 0.728
Toce_0592
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
     
 0.609
Toce_0591
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: csc:Csac_2320 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
  
    0.597
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.538
Toce_0960
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
   
    0.533
Toce_1667
2',3'-cyclic-nucleotide 2'-phosphodiesterase., 5'-nucleotidase; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterProIPR004843:IPR008334:IPR001119:IPR006179:IPR 006146; KEGG: cpo:COPRO5265_0800 multifunctional protein: 5-nucleotidase 2,3-cyclic-nucleotide 2-phosphodiesterase; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; S-layer domain protein; PRIAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase., 5'-nucleotidase; SPTR: Multifunctional protein: 5-nucleotidase 2,3-cyclic-nucleotide 2-phosphodiesterase; PFAM: 5'-nucleotidase, C-termin [...]
 
  
 0.524
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.510
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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