Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0591Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: csc:Csac_2320 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. (239 aa)    
Predicted Functional Partners:
Toce_0592
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
       0.768
Toce_0794
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: dsy:DSY2716 hypothetical protein; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
  
     0.714
Toce_0593
COGs: COG0213 Thymidine phosphorylase; InterProIPR017872:IPR018090:IPR000053:IPR017459:IPR 000312:IPR013102; KEGG: csc:Csac_2318 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; SPTR: Thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase.
     
 0.710
Toce_0588
Nucleoside ABC transporter ATP-binding protein; COGs: COG3845 ABC-type uncharacterized transport systems ATPase components; InterPro IPR003439:IPR017871:IPR003593; KEGG: chy:CHY_1535 putative sugar ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative sugar ABC transporter, ATP-binding protein; PFAM: ABC transporter.
  
    0.703
Toce_0590
Nucleoside ABC transporter membrane protein; COGs: COG1079 ABC-type transport system permease component; InterPro IPR001851; KEGG: chy:CHY_1533 putative sugar ABC transporter, permease protein; PFAM: inner-membrane translocator; SPTR: Putative sugar ABC transporter, permease protein; PFAM: Branched-chain amino acid transport system / permease component.
  
  
 0.693
Toce_0589
Inner-membrane translocator; COGs: COG4603 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: chy:CHY_1534 putative sugar ABC transporter, permease protein; PFAM: inner-membrane translocator; SPTR: Putative sugar ABC transporter, permease protein; PFAM: Branched-chain amino acid transport system / permease component.
       0.678
Toce_1932
InterPro IPR001387:IPR013096; KEGG: drm:Dred_1558 cupin 2 domain-containing protein; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Cupin 2, conserved barrel domain protein; PFAM: Cupin domain; Helix-turn-helix.
  
  
 0.675
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
       0.647
Toce_0587
Nucleoside-binding protein; COGs: COG1744 Uncharacterized ABC-type transport system periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: chy:CHY_1536 basic membrane protein family protein; PFAM: basic membrane lipoprotein; SPTR: Basic membrane protein family protein; PFAM: Basic membrane protein.
  
    0.597
Toce_0578
Cupin 2 conserved barrel domain protein; COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR013096; KEGG: ctc:CTC00439 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Conserved protein; PFAM: Cupin domain.
  
  
 0.539
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.