| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0477 | Toce_0633 | Toce_0477 | Toce_0633 | KEGG: mta:Moth_1792 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2922). | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | 0.402 |
| Toce_0631 | Toce_0632 | Toce_0631 | Toce_0632 | KEGG: tte:TTE0927 hypothetical protein; SPTR: Putative uncharacterized protein. | InterPro IPR000620; KEGG: drm:Dred_1524 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; PFAM: EamA-like transporter family. | 0.522 |
| Toce_0631 | Toce_0633 | Toce_0631 | Toce_0633 | KEGG: tte:TTE0927 hypothetical protein; SPTR: Putative uncharacterized protein. | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | 0.489 |
| Toce_0632 | Toce_0631 | Toce_0632 | Toce_0631 | InterPro IPR000620; KEGG: drm:Dred_1524 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; PFAM: EamA-like transporter family. | KEGG: tte:TTE0927 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.522 |
| Toce_0632 | Toce_0633 | Toce_0632 | Toce_0633 | InterPro IPR000620; KEGG: drm:Dred_1524 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; PFAM: EamA-like transporter family. | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | 0.757 |
| Toce_0632 | tnaA | Toce_0632 | Toce_0634 | InterPro IPR000620; KEGG: drm:Dred_1524 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; PFAM: EamA-like transporter family. | Tryptophanase; COGs: COG3033 Tryptophanase; InterPro IPR011166:IPR001597; KEGG: tte:TTE1602 tryptophanase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Tryptophanase; SPTR: Tryptophanase; PFAM: Beta-eliminating lyase; TIGRFAM: tyrosine phenol-lyase; tryptophanase, leader peptide-associated. | 0.539 |
| Toce_0633 | Toce_0477 | Toce_0633 | Toce_0477 | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | KEGG: mta:Moth_1792 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2922). | 0.402 |
| Toce_0633 | Toce_0631 | Toce_0633 | Toce_0631 | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | KEGG: tte:TTE0927 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.489 |
| Toce_0633 | Toce_0632 | Toce_0633 | Toce_0632 | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | InterPro IPR000620; KEGG: drm:Dred_1524 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; PFAM: EamA-like transporter family. | 0.757 |
| Toce_0633 | Toce_2207 | Toce_0633 | Toce_2207 | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524:IPR004839; KEGG: amt:Amet_3155 GntR family transcriptional regulator; PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator, GntR family; PFAM: Aminotransferase class I and II; Bacterial regulatory proteins, gntR family. | 0.449 |
| Toce_0633 | guaA | Toce_0633 | Toce_0353 | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.646 |
| Toce_0633 | ispH | Toce_0633 | Toce_1156 | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.540 |
| Toce_0633 | tnaA | Toce_0633 | Toce_0634 | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | Tryptophanase; COGs: COG3033 Tryptophanase; InterPro IPR011166:IPR001597; KEGG: tte:TTE1602 tryptophanase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Tryptophanase; SPTR: Tryptophanase; PFAM: Beta-eliminating lyase; TIGRFAM: tyrosine phenol-lyase; tryptophanase, leader peptide-associated. | 0.565 |
| Toce_2207 | Toce_0633 | Toce_2207 | Toce_0633 | COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524:IPR004839; KEGG: amt:Amet_3155 GntR family transcriptional regulator; PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator, GntR family; PFAM: Aminotransferase class I and II; Bacterial regulatory proteins, gntR family. | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | 0.449 |
| guaA | Toce_0633 | Toce_0353 | Toce_0633 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | 0.646 |
| guaA | ispH | Toce_0353 | Toce_1156 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.790 |
| ispH | Toce_0633 | Toce_1156 | Toce_0633 | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | 0.540 |
| ispH | guaA | Toce_1156 | Toce_0353 | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.790 |
| tnaA | Toce_0632 | Toce_0634 | Toce_0632 | Tryptophanase; COGs: COG3033 Tryptophanase; InterPro IPR011166:IPR001597; KEGG: tte:TTE1602 tryptophanase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Tryptophanase; SPTR: Tryptophanase; PFAM: Beta-eliminating lyase; TIGRFAM: tyrosine phenol-lyase; tryptophanase, leader peptide-associated. | InterPro IPR000620; KEGG: drm:Dred_1524 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; PFAM: EamA-like transporter family. | 0.539 |
| tnaA | Toce_0633 | Toce_0634 | Toce_0633 | Tryptophanase; COGs: COG3033 Tryptophanase; InterPro IPR011166:IPR001597; KEGG: tte:TTE1602 tryptophanase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Tryptophanase; SPTR: Tryptophanase; PFAM: Beta-eliminating lyase; TIGRFAM: tyrosine phenol-lyase; tryptophanase, leader peptide-associated. | COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase. | 0.565 |