Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
Toce_0646COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: chy:CHY_1268 glycerate kinase 2; PFAM: glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase 2; TIGRFAM: glycerate kinase; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. (382 aa)    
Predicted Functional Partners:
Toce_0647
Predicted D-glycerate permease (TC 2.A.8.1.6); COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: mta:Moth_0895 gluconate transporter; PFAM: Gluconate transporter; SPTR: Gluconate transporter; PFAM: GntP family permease; TIGRFAM: gluconate transporter.
 
  
 0.913
gpmI
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.912
tadA
tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
    0.904
Toce_0648
Transcriptional regulator, CdaR; COGs: COG3835 Sugar diacid utilization regulator; InterPro IPR008599:IPR002197; KEGG: putative sugar diacid recognition; PFAM: sugar diacid recognition domain protein; helix-turn-helix Fis-type; SPTR: Putative sugar diacid utilization regulator; PFAM: Putative sugar diacid recognition.
 
  
 0.740
Toce_1804
Endoribonuclease L-PSP; COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006056:IPR006175; KEGG: tit:Thit_1447 endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; SPTR: Putative endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP, putative.
      0.682
Toce_0871
COGs: COG0469 Pyruvate kinase; InterProIPR001697:IPR018209:IPR015793:IPR015794:IPR 008279; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.659
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
      0.659
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
    0.638
Toce_0645
Serine-type D-Ala-D-Ala carboxypeptidase; COGs: COG1876 D-alanyl-D-alanine carboxypeptidase; InterPro IPR012854:IPR003709; KEGG: cth:Cthe_1899 M15B family D-Ala-D-Ala carboxypeptidase VanY; PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; copper amine oxidase domain protein; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: Copper amine oxidase N-terminal domain; D-alanyl-D-alanine carboxypeptidase.
       0.501
Toce_1695
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
      
 0.485
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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