STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0647Predicted D-glycerate permease (TC 2.A.8.1.6); COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: mta:Moth_0895 gluconate transporter; PFAM: Gluconate transporter; SPTR: Gluconate transporter; PFAM: GntP family permease; TIGRFAM: gluconate transporter. (461 aa)    
Predicted Functional Partners:
Toce_0646
COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: chy:CHY_1268 glycerate kinase 2; PFAM: glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase 2; TIGRFAM: glycerate kinase; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
 
  
 0.913
xylB
Xylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018483:IPR006000:IPR018484:IPR018485; KEGG: tpd:Teth39_2059 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Xylulokinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase.
 
  
 0.743
Toce_0648
Transcriptional regulator, CdaR; COGs: COG3835 Sugar diacid utilization regulator; InterPro IPR008599:IPR002197; KEGG: putative sugar diacid recognition; PFAM: sugar diacid recognition domain protein; helix-turn-helix Fis-type; SPTR: Putative sugar diacid utilization regulator; PFAM: Putative sugar diacid recognition.
 
   
 0.704
Toce_1896
COGs: COG1023 6-phosphogluconate dehydrogenase; InterPro IPR006183:IPR004849:IPR006115:IPR006114; KEGG: cbk:CLL_A1312 6-phosphogluconate dehydrogenase-like protein; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain; TIGRFAM: 6-phosphogluconate dehydrogenase (decarboxylating); 6-phosphogluconate dehydrogenase, [...]
  
  
 0.556
Toce_0653
COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: tpd:Teth39_1675 type III effector Hrp-dependent outers; PFAM: type III effector Hrp-dependent outers; SPTR: Type III effector Hrp-dependent outers; PFAM: Protein of unknown function, DUF1537.
 
   
 0.526
Toce_0871
COGs: COG0469 Pyruvate kinase; InterProIPR001697:IPR018209:IPR015793:IPR015794:IPR 008279; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.520
Toce_0645
Serine-type D-Ala-D-Ala carboxypeptidase; COGs: COG1876 D-alanyl-D-alanine carboxypeptidase; InterPro IPR012854:IPR003709; KEGG: cth:Cthe_1899 M15B family D-Ala-D-Ala carboxypeptidase VanY; PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; copper amine oxidase domain protein; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: Copper amine oxidase N-terminal domain; D-alanyl-D-alanine carboxypeptidase.
       0.501
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; InterPro IPR005255; KEGG: tpd:Teth39_1674 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.
     
 0.434
Toce_0658
Extracellular solute-binding protein family 5; COGs: COG4166 ABC-type oligopeptide transport system periplasmic component; InterPro IPR000914; KEGG: tpd:Teth39_1689 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: Extracellular solute-binding protein, family 5; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.
  
  
 0.410
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (26%) [HD]