Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Toce_0648Transcriptional regulator, CdaR; COGs: COG3835 Sugar diacid utilization regulator; InterPro IPR008599:IPR002197; KEGG: putative sugar diacid recognition; PFAM: sugar diacid recognition domain protein; helix-turn-helix Fis-type; SPTR: Putative sugar diacid utilization regulator; PFAM: Putative sugar diacid recognition. (392 aa)    
Predicted Functional Partners:
Toce_0646
COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: chy:CHY_1268 glycerate kinase 2; PFAM: glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase 2; TIGRFAM: glycerate kinase; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
 
  
 0.740
Toce_0647
Predicted D-glycerate permease (TC 2.A.8.1.6); COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: mta:Moth_0895 gluconate transporter; PFAM: Gluconate transporter; SPTR: Gluconate transporter; PFAM: GntP family permease; TIGRFAM: gluconate transporter.
 
   
 0.704
Toce_0649
Proprionate catabolism activator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR000014:IPR003593:IPR002078:IPR020441:IPR 010524:IPR013767:IPR002197; KEGG: tpd:Teth39_1679 sigma-54 dependent trancsriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; Propionate catabolism activator domain protein; PAS fold domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; PAS domain containing protein; SPTR: Sigma54 specific transcriptional regulator, Fis family; TIGRFAM: PAS sensor protein; [...]
  
    0.575
Toce_0730
Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR005829:IPR001411:IPR011701; KEGG: mta:Moth_0116 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily.
  
    0.447
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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