STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0649Proprionate catabolism activator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR000014:IPR003593:IPR002078:IPR020441:IPR 010524:IPR013767:IPR002197; KEGG: tpd:Teth39_1679 sigma-54 dependent trancsriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; Propionate catabolism activator domain protein; PAS fold domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; PAS domain containing protein; SPTR: Sigma54 specific transcriptional regulator, Fis family; TIGRFAM: PAS sensor protein; [...] (636 aa)    
Predicted Functional Partners:
Toce_1856
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: pth:PTH_2724 DNA-directed RNA polymerase specialized sigma subunit, sigma54-like protein; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymeras [...]
 
   
 0.784
Toce_0648
Transcriptional regulator, CdaR; COGs: COG3835 Sugar diacid utilization regulator; InterPro IPR008599:IPR002197; KEGG: putative sugar diacid recognition; PFAM: sugar diacid recognition domain protein; helix-turn-helix Fis-type; SPTR: Putative sugar diacid utilization regulator; PFAM: Putative sugar diacid recognition.
       0.566
Toce_0653
COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: tpd:Teth39_1675 type III effector Hrp-dependent outers; PFAM: type III effector Hrp-dependent outers; SPTR: Type III effector Hrp-dependent outers; PFAM: Protein of unknown function, DUF1537.
 
     0.550
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; InterPro IPR005255; KEGG: tpd:Teth39_1674 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.
 
     0.542
Toce_0652
InterPro IPR004684; KEGG: tpd:Teth39_1676 2-keto-3-deoxygluconate permease; PFAM: 2-keto-3-deoxygluconate permease; SPTR: 2-keto-3-deoxygluconate permease; PFAM: 2-keto-3-deoxygluconate permease; TIGRFAM: 2-keto-3-deoxygluconate transporter.
 
     0.536
Toce_0650
SAF domain protein; COGs: COG2721 Altronate dehydratase; InterPro IPR013974; KEGG: tpd:Teth39_1678 SAF domain-containing protein; PFAM: SAF domain protein; SPTR: SAF domain; PFAM: SAF domain.
       0.461
Toce_0651
COGs: COG2721 Altronate dehydratase; InterPro IPR007392; KEGG: tpd:Teth39_1677 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; PRIAM: Altronate dehydratase; SPTR: Altronate dehydratase; PFAM: D-galactarate dehydratase / Altronate hydrolase, C terminus.
       0.461
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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