close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0652InterPro IPR004684; KEGG: tpd:Teth39_1676 2-keto-3-deoxygluconate permease; PFAM: 2-keto-3-deoxygluconate permease; SPTR: 2-keto-3-deoxygluconate permease; PFAM: 2-keto-3-deoxygluconate permease; TIGRFAM: 2-keto-3-deoxygluconate transporter. (321 aa)    
Predicted Functional Partners:
Toce_0653
COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: tpd:Teth39_1675 type III effector Hrp-dependent outers; PFAM: type III effector Hrp-dependent outers; SPTR: Type III effector Hrp-dependent outers; PFAM: Protein of unknown function, DUF1537.
 
   
 0.963
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; InterPro IPR005255; KEGG: tpd:Teth39_1674 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.
 
     0.948
Toce_0650
SAF domain protein; COGs: COG2721 Altronate dehydratase; InterPro IPR013974; KEGG: tpd:Teth39_1678 SAF domain-containing protein; PFAM: SAF domain protein; SPTR: SAF domain; PFAM: SAF domain.
 
    0.870
Toce_0651
COGs: COG2721 Altronate dehydratase; InterPro IPR007392; KEGG: tpd:Teth39_1677 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; PRIAM: Altronate dehydratase; SPTR: Altronate dehydratase; PFAM: D-galactarate dehydratase / Altronate hydrolase, C terminus.
 
    0.865
Toce_1897
COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: tit:Thit_0170 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase.
  
  
 0.715
Toce_0649
Proprionate catabolism activator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR000014:IPR003593:IPR002078:IPR020441:IPR 010524:IPR013767:IPR002197; KEGG: tpd:Teth39_1679 sigma-54 dependent trancsriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; Propionate catabolism activator domain protein; PAS fold domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; PAS domain containing protein; SPTR: Sigma54 specific transcriptional regulator, Fis family; TIGRFAM: PAS sensor protein; [...]
 
     0.536
gatC
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
       0.431
Toce_1029
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
      
 0.414
gatA
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
       0.403
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.