STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0683HEPN domain protein; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: adg:Adeg_0040 HEPN domain protein; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: HEPN domain protein; PFAM: HEPN domain. (139 aa)    
Predicted Functional Partners:
Toce_0682
InterPro IPR002934; KEGG: rrs:RoseRS_4091 DNA polymerase beta subunit; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase, beta domain protein region; PFAM: Nucleotidyltransferase domain.
 
     0.945
Toce_0213
DNA polymerase beta domain protein region; InterPro IPR002934; KEGG: chy:CHY_1716 nucleotidyltransferase/HEPN domain-containing protein; PFAM: DNA polymerase beta domain protein region; SPTR: Nucleotidyltransferase/HEPN domain protein; PFAM: Nucleotidyltransferase domain.
 
 
   0.538
Toce_0681
Hypothetical protein; InterPro IPR011759; KEGG: aae:aq_1502 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.512
Toce_2178
InterPro IPR002934; KEGG: gur:Gura_2470 DNA polymerase beta subunit; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase, beta domain protein region; PFAM: Nucleotidyltransferase domain.
 
     0.512
Toce_0543
HEPN domain protein; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: tye:THEYE_A1691 HEPN domain, putative; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: Hepn domain, putative; PFAM: HEPN domain.
  
     0.443
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.