| node1 | node2 | node1 annotation | node2 annotation | score |
| Toce_0706 | Toce_0707 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | Methyltransferase MtaA/CmuA family; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR006360:IPR000257; KEGG: mmp:MMP0831 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | 0.990 |
| Toce_0706 | Toce_0708 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dae:Dtox_2801 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.835 |
| Toce_0706 | Toce_0709 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | Ferredoxin; COGs: COG3894 Uncharacterized metal-binding protein; InterPro IPR001041; KEGG: swo:Swol_0420 hypothetical protein; PFAM: ferredoxin; SPTR: Putative uncharacterized protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain. | 0.900 |
| Toce_0706 | Toce_0710 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: fpl:Ferp_1758 uroporphyrinogen decarboxylase (URO-D); PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | 0.894 |
| Toce_0706 | Toce_0711 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | Cystathionine beta-synthase (acetylserine-dependent); COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001216:IPR001926; KEGG: gtn:GTNG_2474 O-acetylserine lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.755 |
| Toce_0706 | Toce_0712 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000358:IPR000277; KEGG: gwc:GWCH70_2474 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: cystathionine beta-lyase, eukaryotic. | 0.752 |
| Toce_0706 | Toce_0796 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: amt:Amet_2092 methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; PFAM: dihydropteroate synthase DHPS; SPTR: Dihydropteroate synthase, DHPS; PFAM: Pterin binding enzyme. | 0.977 |
| Toce_0706 | Toce_0812 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: amt:Amet_2027 dihydropteroate synthase, DhpS; PFAM: dihydropteroate synthase DHPS; SPTR: Dihydropteroate synthase, DHPS; PFAM: Pterin binding enzyme. | 0.971 |
| Toce_0706 | Toce_1080 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: mta:Moth_2115 methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; PFAM: dihydropteroate synthase DHPS; PRIAM: Methionine synthase; SPTR: 5-methyltetrahydrofolate--homocysteine S-methyltransferase; PFAM: Pterin binding enzyme. | 0.978 |
| Toce_0706 | Toce_1535 | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | COGs: COG1962 Tetrahydromethanopterin S-methyltransferase subunit H; InterPro IPR002856; KEGG: mch:Mchl_5727 tetrahydromethanopterin S-methyltransferase subunit H; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; PRIAM: Tetrahydromethanopterin S-methyltransferase; SPTR: CmuB; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; TIGRFAM: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H. | 0.909 |
| Toce_0707 | Toce_0706 | Methyltransferase MtaA/CmuA family; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR006360:IPR000257; KEGG: mmp:MMP0831 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | 0.990 |
| Toce_0707 | Toce_0708 | Methyltransferase MtaA/CmuA family; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR006360:IPR000257; KEGG: mmp:MMP0831 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dae:Dtox_2801 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.913 |
| Toce_0707 | Toce_0709 | Methyltransferase MtaA/CmuA family; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR006360:IPR000257; KEGG: mmp:MMP0831 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | Ferredoxin; COGs: COG3894 Uncharacterized metal-binding protein; InterPro IPR001041; KEGG: swo:Swol_0420 hypothetical protein; PFAM: ferredoxin; SPTR: Putative uncharacterized protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain. | 0.932 |
| Toce_0707 | Toce_0710 | Methyltransferase MtaA/CmuA family; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR006360:IPR000257; KEGG: mmp:MMP0831 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: fpl:Ferp_1758 uroporphyrinogen decarboxylase (URO-D); PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | 0.836 |
| Toce_0707 | Toce_0711 | Methyltransferase MtaA/CmuA family; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR006360:IPR000257; KEGG: mmp:MMP0831 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | Cystathionine beta-synthase (acetylserine-dependent); COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001216:IPR001926; KEGG: gtn:GTNG_2474 O-acetylserine lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.780 |
| Toce_0707 | Toce_0712 | Methyltransferase MtaA/CmuA family; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR006360:IPR000257; KEGG: mmp:MMP0831 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000358:IPR000277; KEGG: gwc:GWCH70_2474 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: cystathionine beta-lyase, eukaryotic. | 0.774 |
| Toce_0707 | Toce_1535 | Methyltransferase MtaA/CmuA family; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR006360:IPR000257; KEGG: mmp:MMP0831 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | COGs: COG1962 Tetrahydromethanopterin S-methyltransferase subunit H; InterPro IPR002856; KEGG: mch:Mchl_5727 tetrahydromethanopterin S-methyltransferase subunit H; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; PRIAM: Tetrahydromethanopterin S-methyltransferase; SPTR: CmuB; PFAM: Tetrahydromethanopterin S-methyltransferase MtrH subunit; TIGRFAM: N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H. | 0.921 |
| Toce_0708 | Toce_0706 | COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dae:Dtox_2801 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family. | 0.835 |
| Toce_0708 | Toce_0707 | COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dae:Dtox_2801 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | Methyltransferase MtaA/CmuA family; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR006360:IPR000257; KEGG: mmp:MMP0831 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. | 0.913 |
| Toce_0708 | Toce_0709 | COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dae:Dtox_2801 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | Ferredoxin; COGs: COG3894 Uncharacterized metal-binding protein; InterPro IPR001041; KEGG: swo:Swol_0420 hypothetical protein; PFAM: ferredoxin; SPTR: Putative uncharacterized protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain. | 0.924 |