Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Toce_0734Copper ion binding protein; COGs: COG2608 Copper chaperone; InterPro IPR006121:IPR006122:IPR017969:IPR001802; KEGG: nth:Nther_1097 copper ion binding protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Copper ion binding protein; TIGRFAM: copper ion binding protein; PFAM: Heavy-metal-associated domain; TIGRFAM: copper ion binding protein. (79 aa)    
Predicted Functional Partners:
Toce_0722
Copper-translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR006403:IPR006416:IPR001757:IPR 018303:IPR017969:IPR001756:IPR001877:IPR008250:IPR005834; KEGG: tte:TTE2463 cation transport ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Copper-translocating P-type ATPase; TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-as [...]
 
 
 0.947
Toce_1727
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; Contains selenocysteine; InterProIPR006404:IPR006416:IPR001757:IPR006121:IPR 008250:IPR005834:IPR001366:IPR018303; KEGG: gsu:GSU2147 cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; manual [...]
 
 
 0.921
Toce_0329
Transcriptional repressor, CopY family; COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: cbe:Cbei_1062 CopY family transcriptional regulator; PFAM: Penicillinase repressor; SPTR: Transcriptional repressor, CopY family; PFAM: Penicillinase repressor.
  
  
 0.772
Toce_1357
Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: dhd:Dhaf_3585 protein of unknown function DUF156; PFAM: protein of unknown function DUF156; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937.
  
  
 0.727
Toce_0735
Protein of unknown function DUF1312; COGs: COG5341 conserved hypothetical protein; InterPro IPR010739; KEGG: tpd:Teth39_2118 hypothetical protein; PFAM: protein of unknown function DUF1312; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1312).
 
     0.544
rplN
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.505
Toce_0733
BioY protein; COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: tte:TTE0777 uncharacterized ACR; PFAM: BioY protein; SPTR: Uncharacterized ACR; PFAM: BioY family.
       0.495
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
      
 0.471
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
   0.468
Toce_0736
Heptaprenyl diphosphate synthase component I; COGs: COG4769 membrane protein; InterPro IPR014535:IPR010898; KEGG: aoe:Clos_1769 heptaprenyl diphosphate synthase component I; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: Heptaprenyl diphosphate synthase component I; PFAM: Heptaprenyl diphosphate synthase component I.
       0.437
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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