STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0743Penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR017790:IPR018247:IPR005311:IPR001460; KEGG: chy:CHY_0345 peptidoglycan biosynthesis transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2. (695 aa)    
Predicted Functional Partners:
rodA
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.991
Toce_0741
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.981
Toce_0740
Rod shape-determining protein MreB; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: amt:Amet_2290 rod shape-determining protein MreB; PFAM: cell shape determining protein MreB/Mrl; SPTR: Cell shape determining protein, MreB/Mrl family; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family.
 
 0.967
Toce_0951
Spore cortex peptidoglycan biosynthesis regulator SpoVE; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR013437:IPR013438; KEGG: afl:Aflv_1831 stage V sporulation protein E required for spore cortex peptidoglycan synthesis; PFAM: cell cycle protein; SPTR: Stage V sporulation protein E required for spore cortex peptidoglycan synthesis; TIGRFAM: stage V sporulation protein E; cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: stage V sporulation protein E; cell division protein FtsW; Belongs to the SEDS family.
 
 0.947
Toce_1339
COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: tit:Thit_1052 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain.
  
  
0.926
Toce_0253
Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: tpd:Teth39_0572 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family.
 
 0.870
Toce_0742
Rod shape-determining protein MreD; InterPro IPR007227:IPR017225; KEGG: dae:Dtox_3337 rod shape-determining protein MreD; SPTR: Rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD; PFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD.
  
  
 0.862
Toce_0955
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
 
 
 0.859
Toce_2012
Rod shape-determining protein MreB; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: cth:Cthe_2619 rod shape-determining protein Mbl; PFAM: cell shape determining protein MreB/Mrl; SPTR: Cell shape determining protein, MreB/Mrl family; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family.
 
 0.859
Toce_0042
Cyanophycin synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterProIPR011810:IPR005479:IPR013221:IPR004101:IPR 018109:IPR011761; KEGG: tte:TTE2785 cyanophycin synthetase; PFAM: Mur ligase middle domain protein; Carbamoyl-phosphate synthase L chain ATP-binding; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramyl tripeptide synthase; TIGRFAM: cyanophycin synthetase; PFAM: RimK-like ATP-grasp domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Str [...]
  
 
 0.780
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (34%) [HD]