Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_0748Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tte:TTE0907 membrane proteins related to metalloendopeptidase; PFAM: Peptidase M23; SPTR: Membrane proteins related to metalloendopeptidases; PFAM: Peptidase family M23. (237 aa)    
Predicted Functional Partners:
Toce_0749
Peptidase M50; InterPro IPR008915; KEGG: nth:Nther_0524 peptidase M50; PFAM: peptidase M50; SPTR: Peptidase M50; PFAM: Peptidase family M50.
       0.763
Toce_0751
Protein of unknown function DUF2344; COGs: COG5011 conserved hypothetical protein; InterPro IPR018768; KEGG: dau:Daud_1454 hypothetical protein; PFAM: Protein of unknown function DUF2344; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344).
       0.705
Toce_0750
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: tit:Thit_0845 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
  
    0.694
Toce_1110
COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR001172:IPR007597:IPR001543:IPR012826; KEGG: tte:TTE1429 flagellar motor switch protein; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; SPTR: Chemotaxis protein CheC, inhibitor of MCP methylation; TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); CheC-like family; TIGRFAM: flagellar motor switch protein FliN.
   
   0.690
Toce_1390
Penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR011816:IPR001264:IPR001460:IPR002119; KEGG: chy:CHY_1563 1A family penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family.
  
  
 0.686
Toce_0752
COGs: COG1530 Ribonuclease G and E; InterProIPR003029:IPR002792:IPR004659:IPR018247:IPR 000463:IPR019307; KEGG: sth:STH426 ribonuclease G; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein; deoxyribonuclease/rho motif-related TRAM; SPTR: Ribonuclease G; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; TRAM domain; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family.
  
  
 0.673
rodA
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
     
 0.528
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
  
    0.507
Toce_0745
Septum site-determining protein MinD; COGs: COG2894 Septum formation inhibitor-activating ATPase; InterPro IPR010223; KEGG: dhd:Dhaf_4346 septum site-determining protein MinD; SPTR: Putative uncharacterized protein; TIGRFAM: septum site-determining protein MinD; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD.
       0.440
Toce_1339
COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: tit:Thit_1052 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; SPTR: Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain.
 
   
 0.429
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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