Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_0751Protein of unknown function DUF2344; COGs: COG5011 conserved hypothetical protein; InterPro IPR018768; KEGG: dau:Daud_1454 hypothetical protein; PFAM: Protein of unknown function DUF2344; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344). (224 aa)    
Predicted Functional Partners:
Toce_0750
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: tit:Thit_0845 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
    0.995
Toce_0965
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR006158:IPR007197; KEGG: vpr:Vpar_1433 radical SAM domain protein; PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; B12 binding domain.
    0.977
Toce_0752
COGs: COG1530 Ribonuclease G and E; InterProIPR003029:IPR002792:IPR004659:IPR018247:IPR 000463:IPR019307; KEGG: sth:STH426 ribonuclease G; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein; deoxyribonuclease/rho motif-related TRAM; SPTR: Ribonuclease G; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; TRAM domain; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family.
       0.798
Toce_0748
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tte:TTE0907 membrane proteins related to metalloendopeptidase; PFAM: Peptidase M23; SPTR: Membrane proteins related to metalloendopeptidases; PFAM: Peptidase family M23.
       0.705
Toce_0749
Peptidase M50; InterPro IPR008915; KEGG: nth:Nther_0524 peptidase M50; PFAM: peptidase M50; SPTR: Peptidase M50; PFAM: Peptidase family M50.
       0.673
rodA
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
       0.471
Toce_0753
Transposase IS4 family protein; COGs: COG3666 Transposase and inactivated derivatives; InterPro IPR002559; KEGG: tte:TTE2646 transposase; PFAM: transposase IS4 family protein; SPTR: Transposase; PFAM: Transposase DDE domain; Transposase domain (DUF772).
       0.452
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
       0.437
Toce_0745
Septum site-determining protein MinD; COGs: COG2894 Septum formation inhibitor-activating ATPase; InterPro IPR010223; KEGG: dhd:Dhaf_4346 septum site-determining protein MinD; SPTR: Putative uncharacterized protein; TIGRFAM: septum site-determining protein MinD; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD.
       0.431
polC
DNA polymerase III catalytic subunit, PolC type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
    0.425
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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