STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0766Hypothetical protein; KEGG: dae:Dtox_0401 signal transduction histidine kinase regulating citrate/malate metabolism; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism. (209 aa)    
Predicted Functional Partners:
obg
GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.638
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
       0.605
rpmA
COGs: COG0211 Ribosomal protein L27; InterPro IPR001684:IPR018261; KEGG: tpd:Teth39_1433 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: Ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
       0.605
Toce_0764
Protein of unknown function DUF464; COGs: COG2868 ribosomal protein; InterPro IPR007422; KEGG: cth:Cthe_0161 hypothetical protein; PFAM: protein of unknown function DUF464; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF464).
       0.601
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
       0.507
Toce_0769
Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR003607:IPR005249:IPR006675:IPR006674; KEGG: tte:TTE0919 HD superfamily hydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Predicted HD superfamily hydrolase involved in NAD metabolism; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: conserved hypothetical protein TIGR00488; uncharacterized domain HDIG.
       0.495
Toce_0770
Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: tte:TTE0920 transcriptional regulator; PFAM: cell envelope-related transcriptional attenuator; SPTR: Transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain.
       0.481
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
       0.469
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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