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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0796Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: amt:Amet_2092 methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; PFAM: dihydropteroate synthase DHPS; SPTR: Dihydropteroate synthase, DHPS; PFAM: Pterin binding enzyme. (271 aa)    
Predicted Functional Partners:
Toce_0811
COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR016218:IPR007202:IPR016041; KEGG: amt:Amet_2026 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit.
 
 0.994
Toce_0810
COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: amt:Amet_2025 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit.
 
 
 0.992
Toce_1078
Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR003759:IPR006158:IPR012741; KEGG: mta:Moth_1208 5-methyltetrahydrofolate--homocysteine S-methyltransferase; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; PRIAM: Methionine synthase; SPTR: 5-methyltetrahydrofolate--homocysteine S-methyltransferase; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family.
  
 0.978
Toce_0706
Methyltransferase cognate corrinoid protein; COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759:IPR012741; KEGG: swo:Swol_0418 cobalamin-dependent methionine synthase, B12-binding; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Dimethylamine corrinoid protein; TIGRFAM: methyltransferase cognate corrinoid protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family.
  
 0.977
Toce_0790
COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: amt:Amet_2093 cobalamin B12-binding domain-containing protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Cobalamin B12-binding domain protein; PFAM: B12 binding domain.
  
 0.977
Toce_0793
COGs: COG5012 cobalamin binding protein; InterPro IPR006158:IPR003759; KEGG: amt:Amet_2097 cobalamin B12-binding domain-containing protein; PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; SPTR: Cobalamin B12-binding domain protein; PFAM: B12 binding domain.
  
 0.977
Toce_1081
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dhd:Dhaf_0077 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylene-tetrahydrofolate reductase C terminal; Methylenetetrahydrofolate reductase.
 
 
 0.971
Toce_0813
COGs: COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit; InterPro IPR004461; KEGG: cdl:CDR20291_0655 putative carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; SPTR: Putative carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit.
 
  
 0.968
Toce_0807
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: amt:Amet_2022 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.963
fhs
Formate-tetrahydrofolate ligase; COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR020628:IPR000559; KEGG: ckr:CKR_0385 hypothetical protein; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: Formate--tetrahydrofolate ligase; SPTR: Formate--tetrahydrofolate ligase; PFAM: Formate--tetrahydrofolate ligase.
    
 0.941
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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