STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0803Protein of unknown function DUF166; COGs: COG1810 conserved hypothetical protein; InterPro IPR003745; KEGG: mfs:MFS40622_1422 protein of unknown function DUF166; PFAM: Protein of unknown function DUF166; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ArCR, COG1810. (277 aa)    
Predicted Functional Partners:
Toce_0804
Formimidoyltetrahydrofolate cyclodeaminase; COGs: COG3404 Methenyl tetrahydrofolate cyclohydrolase; InterPro IPR007044; KEGG: cdf:CD0719 methenyltetrahydrofolate cyclohydrolase; PFAM: Formiminotransferase-cyclodeaminase; PRIAM: Glutamate formimidoyltransferase; SPTR: Methenyltetrahydrofolate cyclohydrolase; PFAM: Formiminotransferase-cyclodeaminase.
       0.773
fhs
Formate-tetrahydrofolate ligase; COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR020628:IPR000559; KEGG: ckr:CKR_0385 hypothetical protein; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: Formate--tetrahydrofolate ligase; SPTR: Formate--tetrahydrofolate ligase; PFAM: Formate--tetrahydrofolate ligase.
       0.613
Toce_0809
Cobyrinic acid a,c-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR014433; KEGG: amt:Amet_2024 cobyrinic acid a,c-diamide synthase; SPTR: Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
       0.590
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.572
Toce_0806
KEGG: cdl:CDR20291_0648 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Methylene-tetrahydrofolate reductase C terminal.
       0.572
Toce_0807
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: amt:Amet_2022 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
       0.572
Toce_0808
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR006258:IPR012999:IPR013027:IPR000815:IPR 004099; KEGG: amt:Amet_2023 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
       0.572
Toce_0810
COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: amt:Amet_2025 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit.
       0.532
Toce_0811
COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR016218:IPR007202:IPR016041; KEGG: amt:Amet_2026 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit.
       0.479
Toce_0813
COGs: COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit; InterPro IPR004461; KEGG: cdl:CDR20291_0655 putative carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; SPTR: Putative carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit.
       0.444
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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