Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0815Ferredoxin; COGs: COG3894 Uncharacterized metal-binding protein; InterPro IPR001041; KEGG: amt:Amet_2030 ferredoxin; PFAM: ferredoxin; SPTR: Ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain. (648 aa)    
Predicted Functional Partners:
Toce_0811
COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR016218:IPR007202:IPR016041; KEGG: amt:Amet_2026 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit.
 
 
 0.972
Toce_0810
COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041; KEGG: amt:Amet_2025 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit.
 
 
 
 0.964
Toce_0813
COGs: COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit; InterPro IPR004461; KEGG: cdl:CDR20291_0655 putative carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; SPTR: Putative carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit.
 
   
 0.901
Toce_0809
Cobyrinic acid a,c-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR014433; KEGG: amt:Amet_2024 cobyrinic acid a,c-diamide synthase; SPTR: Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
   
 0.824
Toce_0806
KEGG: cdl:CDR20291_0648 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Methylene-tetrahydrofolate reductase C terminal.
 
   
 0.788
Toce_0801
Cobyrinic acid a,c-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR014433; KEGG: amt:Amet_2017 cobyrinic acid a,c-diamide synthase; SPTR: Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
   
 0.751
Toce_0816
RNA-binding protein, predicted; InterPro IPR019300; KEGG: amt:Amet_2034 hypothetical protein; PFAM: RNA-binding protein, predicted; SPTR: Putative uncharacterized protein; PFAM: Predicted RNA-binding protein.
 
     0.744
Toce_0807
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: amt:Amet_2022 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
     0.632
Toce_0708
COGs: COG0407 Uroporphyrinogen-III decarboxylase; KEGG: dae:Dtox_2801 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D).
 
    0.613
Toce_0707
Methyltransferase MtaA/CmuA family; COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR006360:IPR000257; KEGG: mmp:MMP0831 methylcobalamin:coenzyme M methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family.
 
    0.601
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (20%) [HD]