STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0831COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006095:IPR016211:IPR006097:IPR006096; KEGG: sth:STH1827 leucine dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase dimerisation region; Glu/Leu/Phe/Val dehydrogenase; SPTR: Leucine dehydrogenase; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (345 aa)    
Predicted Functional Partners:
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.918
Toce_1567
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096:IPR006095:IPR016211; KEGG: nth:Nther_2349 leucine dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase dimerisation region; Glu/Leu/Phe/Val dehydrogenase; SPTR: Leucine dehydrogenase; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 
0.905
buk
COGs: COG3426 Butyrate kinase; InterPro IPR011245:IPR000890; KEGG: aoe:Clos_2413 butyrate kinase; PFAM: acetate and butyrate kinase; SPTR: Butyrate kinase; TIGRFAM: butyrate kinase; PFAM: Acetokinase family; TIGRFAM: butyrate kinase; Belongs to the acetokinase family.
  
  
 0.858
Toce_0830
Phosphate butyryltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR012147:IPR002505; KEGG: nth:Nther_1682 phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate butyryltransferase; SPTR: Phosphate butyryltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate butyryltransferase.
  
  
 0.808
buk-2
COGs: COG3426 Butyrate kinase; InterPro IPR011245:IPR000890; KEGG: tpd:Teth39_0462 butyrate kinase; PFAM: acetate and butyrate kinase; SPTR: Acetate and butyrate kinase; TIGRFAM: butyrate kinase; PFAM: Acetokinase family; TIGRFAM: butyrate kinase; Belongs to the acetokinase family.
  
  
 0.740
lon
ATP-dependent proteinase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
 
  0.620
Toce_0871
COGs: COG0469 Pyruvate kinase; InterProIPR001697:IPR018209:IPR015793:IPR015794:IPR 008279; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.602
Toce_1047
COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR012147:IPR004614; KEGG: tte:TTE1482 phosphotransacetylase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase; SPTR: Phosphotransacetylase; TIGRFAM: phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase.
  
  
 0.590
Toce_1565
Phosphate butyryltransferase; COGs: COG0280 Phosphotransacetylase; InterPro IPR002505:IPR012147; KEGG: tte:TTE2204 phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate butyryltransferase; SPTR: Phosphotransacetylase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate butyryltransferase.
  
  
 0.590
Toce_0560
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR012408:IPR015590; KEGG: tex:Teth514_1942 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family.
  
 0.564
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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