Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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Toce_0843Beta-lactamase domain protein; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); KEGG: dae:Dtox_2072 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily. (295 aa)    
Predicted Functional Partners:
Toce_0842
KEGG: gwc:GWCH70_3435 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3006).
 
     0.871
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      0.758
cinA
Competence/damage-inducible protein cinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: dtu:Dtur_0064 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor [...]
      
 0.474
Toce_0773
Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR003583:IPR004509:IPR019554:IPR000445; KEGG: mta:Moth_0570 competence protein ComEA helix-hairpin-helix region; PFAM: Soluble ligand binding domain; helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1; SPTR: Competence protein ComEA helix-hairpin-helix region; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; Helix-hairpin-helix motif; TIGRFAM: competence protein ComEA helix-hairpin-helix r [...]
 
  
 0.418
Toce_0844
Protein of unknown function DUF1540; InterPro IPR011437; KEGG: cac:CAC0521 hypothetical protein; PFAM: protein of unknown function DUF1540; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1540).
       0.401
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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