Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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Toce_0861Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: dau:Daud_0172 hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Haloacid dehalogenase domain protein hydrolase; PFAM: haloacid dehalogenase-like hydrolase. (238 aa)    
Predicted Functional Partners:
Toce_0860
KEGG: sth:STH1710 hypothetical protein; SPTR: UPF0342 protein STH1710; PFAM: Protein of unknown function (DUF964); Belongs to the UPF0342 family.
 
     0.808
Toce_0859
COGs: COG1092 SAM-dependent methyltransferase; InterPro IPR002478:IPR002905; KEGG: cpi:Cpin_6903 putative RNA methylase; PFAM: N2N2-dimethylguanosine tRNA methyltransferase; PUA domain containing protein; SMART: PUA domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PUA domain; S-adenosylmethionine-dependent methyltransferase.
       0.773
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
  
 
 0.709
Toce_1695
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.659
lon
ATP-dependent proteinase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
 
  0.611
Toce_0864
Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
       0.561
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.555
Toce_1274
NUDIX hydrolase; InterPro IPR000086:IPR020084; KEGG: tte:TTE1310 NTP pyrophosphohydrolase including oxidative damage repair enzyme; PFAM: NUDIX hydrolase; SPTR: NTP pyrophosphohydrolases including oxidative damage repair enzymes; PFAM: NUDIX domain; TIGRFAM: nudix hydrolase, YffH family.
  
 
 0.546
Toce_0862
COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR003141:IPR010140:IPR004013; KEGG: tte:TTE1835 PHP family histidinol phosphatase/hydrolase; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: Histidinol phosphatase and related hydrolases of the PHP family; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family.
  
    0.535
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.531
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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