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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Toce_0864Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (312 aa)    
Predicted Functional Partners:
Toce_0863
Conserved hypothetical protein; Displays ATPase and GTPase activities.
  
  
 0.978
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
  
  
 0.926
Toce_0862
COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR003141:IPR010140:IPR004013; KEGG: tte:TTE1835 PHP family histidinol phosphatase/hydrolase; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: Histidinol phosphatase and related hydrolases of the PHP family; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family.
       0.792
Toce_0866
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR000032:IPR005698:IPR001020:IPR002114; KEGG: tte:TTE1820 phosphotransferase system, HPr-related proteins; PFAM: phosphoryl transfer system HPr; SPTR: Phosphotransferase system, HPr-related proteins; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
  
  
 0.751
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.696
Toce_0871
COGs: COG0469 Pyruvate kinase; InterProIPR001697:IPR018209:IPR015793:IPR015794:IPR 008279; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
       0.618
Toce_0867
Putative signal transduction protein with CBS and DRTGG domains; COGs: COG4109 transcriptional regulator protein containing CBS domains; InterPro IPR000644:IPR010766; KEGG: gwc:GWCH70_2695 putative signal transduction protein with CBS and DRTGG domains; PFAM: DRTGG domain protein; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Putative signal transduction protein with CBS and DRTGG domains; PFAM: DRTGG domain; CBS domain; Bacterial regulatory proteins, gntR family.
       0.615
Toce_0868
DNA polymerase III catalytic subunit, DnaE type; COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR003141:IPR004805:IPR004013:IPR011708:IPR 004365; KEGG: tte:TTE1818 DNA polymerase III DnaE; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directe [...]
       0.609
Toce_0861
Haloacid dehalogenase domain protein hydrolase; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: dau:Daud_0172 hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Haloacid dehalogenase domain protein hydrolase; PFAM: haloacid dehalogenase-like hydrolase.
       0.561
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
       0.534
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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