Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Toce_0892COGs: COG4912 DNA alkylation repair protein; InterPro IPR014825; KEGG: hor:Hore_01880 DNA alkylation repair enzyme; PFAM: DNA alkylation repair enzyme; SPTR: DNA alkylation repair enzyme; PFAM: DNA alkylation repair enzyme. (237 aa)    
Predicted Functional Partners:
Toce_0893
Xylose isomerase domain protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: ctc:CTC00572 hypothetical protein; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: Conserved protein; PFAM: Xylose isomerase-like TIM barrel.
       0.648
Toce_0894
ADP-ribosylation/Crystallin J1; COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: sti:Sthe_0600 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1; SPTR: ADP-ribosylation/Crystallin J1; manually curated; PFAM: ADP-ribosylglycohydrolase.
       0.470
Toce_1360
HtrA2 peptidase; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254:IPR001478:IPR001940; KEGG: dae:Dtox_0986 HtrA2 peptidase; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF domain protein; SPTR: HtrA2 peptidase; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family.
  
    0.404
Toce_1687
PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: tpd:Teth39_0567 PDZ/DHR/GLGF domain-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: PDZ/DHR/GLGF domain protein; PFAM: PDZ domain (Also known as DHR or GLGF).
  
    0.404
Toce_0891
KEGG: dau:Daud_0054 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.401
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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