Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0893Xylose isomerase domain protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: ctc:CTC00572 hypothetical protein; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: Conserved protein; PFAM: Xylose isomerase-like TIM barrel. (264 aa)    
Predicted Functional Partners:
Toce_0892
COGs: COG4912 DNA alkylation repair protein; InterPro IPR014825; KEGG: hor:Hore_01880 DNA alkylation repair enzyme; PFAM: DNA alkylation repair enzyme; SPTR: DNA alkylation repair enzyme; PFAM: DNA alkylation repair enzyme.
       0.648
Toce_0894
ADP-ribosylation/Crystallin J1; COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: sti:Sthe_0600 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1; SPTR: ADP-ribosylation/Crystallin J1; manually curated; PFAM: ADP-ribosylglycohydrolase.
     
 0.578
Toce_1367
Von Willebrand factor type A; COGs: COG1240 Mg-chelatase subunit ChlD; InterPro IPR002035; KEGG: nth:Nther_2026 von Willebrand factor type A; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Von Willebrand factor, type A; PFAM: von Willebrand factor type A domain.
 
    0.553
Toce_1876
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611; KEGG: ypz:YPZ3_1906 putative sugar kinase; PFAM: PfkB domain protein; SPTR: Putative sugar kinase; PFAM: pfkB family carbohydrate kinase.
  
  
 0.518
Toce_1590
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: tte:TTE0653 dehydrogenase and related proteins; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Predicted dehydrogenases and related proteins; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
  
  
 0.513
Toce_0238
COGs: COG5423 metal-binding protein; InterPro IPR019271; KEGG: pth:PTH_2051 hypothetical protein; PFAM: Protein of unknown function DUF2284, metal-binding; SPTR: Putative uncharacterized protein; PFAM: Predicted metal-binding protein (DUF2284).
  
     0.449
Toce_1880
Copper amine oxidase domain protein; COGs: COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase; InterPro IPR012854; KEGG: tit:Thit_0459 hypothetical protein; PFAM: copper amine oxidase domain protein; SPTR: Putative uncharacterized protein; PFAM: Copper amine oxidase N-terminal domain; Predicted periplasmic protein (DUF2233).
  
     0.422
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
 
   
 0.418
Toce_0791
KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D).
  
    0.402
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (16%) [HD]