| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0102 | Toce_0934 | Toce_0102 | Toce_0934 | COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR014249:IPR002797; KEGG: amt:Amet_0163 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B. | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | 0.570 |
| Toce_0102 | Toce_1354 | Toce_0102 | Toce_1354 | COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR014249:IPR002797; KEGG: amt:Amet_0163 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B. | Protein of unknown function DUF965; COGs: COG4472 conserved hypothetical protein; InterPro IPR009309; KEGG: dae:Dtox_2267 protein of unknown function DUF965; PFAM: protein of unknown function DUF965; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF965); Belongs to the UPF0297 family. | 0.724 |
| Toce_0102 | Toce_2258 | Toce_0102 | Toce_2258 | COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR014249:IPR002797; KEGG: amt:Amet_0163 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B. | Protein of unknown function DUF951; COGs: COG4481 conserved hypothetical protein; InterPro IPR009296; KEGG: cth:Cthe_2512 hypothetical protein; PFAM: protein of unknown function DUF951; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF951). | 0.457 |
| Toce_0934 | Toce_0102 | Toce_0934 | Toce_0102 | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR014249:IPR002797; KEGG: amt:Amet_0163 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B. | 0.570 |
| Toce_0934 | Toce_0935 | Toce_0934 | Toce_0935 | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | Protein of unknown function DUF34; COGs: COG3323 conserved hypothetical protein; InterPro IPR002678:IPR017221; KEGG: tit:Thit_1543 protein of unknown function DUF34; PFAM: protein of unknown function DUF34; SPTR: Putative uncharacterized protein; manually curated; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | 0.996 |
| Toce_0934 | Toce_1017 | Toce_0934 | Toce_1017 | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: tte:TTE1517 RNA-binding protein snRNP; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Predicted RNA-binding protein homologous to eukaryotic snRNP; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA). | 0.663 |
| Toce_0934 | Toce_1354 | Toce_0934 | Toce_1354 | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | Protein of unknown function DUF965; COGs: COG4472 conserved hypothetical protein; InterPro IPR009309; KEGG: dae:Dtox_2267 protein of unknown function DUF965; PFAM: protein of unknown function DUF965; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF965); Belongs to the UPF0297 family. | 0.752 |
| Toce_0934 | Toce_2253 | Toce_0934 | Toce_2253 | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | 0.613 |
| Toce_0934 | Toce_2258 | Toce_0934 | Toce_2258 | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | Protein of unknown function DUF951; COGs: COG4481 conserved hypothetical protein; InterPro IPR009296; KEGG: cth:Cthe_2512 hypothetical protein; PFAM: protein of unknown function DUF951; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF951). | 0.585 |
| Toce_0934 | dnaG | Toce_0934 | Toce_0931 | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.542 |
| Toce_0934 | mrnC | Toce_0934 | Toce_2113 | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | Ribonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.568 |
| Toce_0934 | sigA | Toce_0934 | Toce_0933 | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.685 |
| Toce_0934 | whiA | Toce_0934 | Toce_0865 | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | Protein of unknown function DUF199; Involved in cell division and chromosome segregation. | 0.615 |
| Toce_0935 | Toce_0934 | Toce_0935 | Toce_0934 | Protein of unknown function DUF34; COGs: COG3323 conserved hypothetical protein; InterPro IPR002678:IPR017221; KEGG: tit:Thit_1543 protein of unknown function DUF34; PFAM: protein of unknown function DUF34; SPTR: Putative uncharacterized protein; manually curated; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | 0.996 |
| Toce_0935 | dnaG | Toce_0935 | Toce_0931 | Protein of unknown function DUF34; COGs: COG3323 conserved hypothetical protein; InterPro IPR002678:IPR017221; KEGG: tit:Thit_1543 protein of unknown function DUF34; PFAM: protein of unknown function DUF34; SPTR: Putative uncharacterized protein; manually curated; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.704 |
| Toce_0935 | sigA | Toce_0935 | Toce_0933 | Protein of unknown function DUF34; COGs: COG3323 conserved hypothetical protein; InterPro IPR002678:IPR017221; KEGG: tit:Thit_1543 protein of unknown function DUF34; PFAM: protein of unknown function DUF34; SPTR: Putative uncharacterized protein; manually curated; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. | RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.763 |
| Toce_1017 | Toce_0934 | Toce_1017 | Toce_0934 | COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: tte:TTE1517 RNA-binding protein snRNP; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Predicted RNA-binding protein homologous to eukaryotic snRNP; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA). | Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: ckr:CKR_0857 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633). | 0.663 |
| Toce_1017 | Toce_1354 | Toce_1017 | Toce_1354 | COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: tte:TTE1517 RNA-binding protein snRNP; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Predicted RNA-binding protein homologous to eukaryotic snRNP; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA). | Protein of unknown function DUF965; COGs: COG4472 conserved hypothetical protein; InterPro IPR009309; KEGG: dae:Dtox_2267 protein of unknown function DUF965; PFAM: protein of unknown function DUF965; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF965); Belongs to the UPF0297 family. | 0.706 |
| Toce_1017 | Toce_2258 | Toce_1017 | Toce_2258 | COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: tte:TTE1517 RNA-binding protein snRNP; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Predicted RNA-binding protein homologous to eukaryotic snRNP; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA). | Protein of unknown function DUF951; COGs: COG4481 conserved hypothetical protein; InterPro IPR009296; KEGG: cth:Cthe_2512 hypothetical protein; PFAM: protein of unknown function DUF951; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF951). | 0.516 |
| Toce_1017 | mrnC | Toce_1017 | Toce_2113 | COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: tte:TTE1517 RNA-binding protein snRNP; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Predicted RNA-binding protein homologous to eukaryotic snRNP; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA). | Ribonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.614 |