| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0289 | Toce_0466 | Toce_0289 | Toce_0466 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | 0.930 |
| Toce_0289 | Toce_1915 | Toce_0289 | Toce_1915 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.919 |
| Toce_0289 | ddl | Toce_0289 | Toce_0210 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.950 |
| Toce_0289 | murD | Toce_0289 | Toce_0950 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.482 |
| Toce_0289 | murE | Toce_0289 | Toce_0947 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.403 |
| Toce_0289 | murF | Toce_0289 | Toce_0948 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.945 |
| Toce_0466 | Toce_0289 | Toce_0466 | Toce_0289 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.930 |
| Toce_0466 | Toce_0946 | Toce_0466 | Toce_0946 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543:IPR005311:IPR001460:IPR011927; KEGG: hor:Hore_09030 stage V sporulation protein D; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Stage V sporulation protein D; TIGRFAM: stage V sporulation protein D; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: sta [...] | 0.515 |
| Toce_0466 | Toce_0951 | Toce_0466 | Toce_0951 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | Spore cortex peptidoglycan biosynthesis regulator SpoVE; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR013437:IPR013438; KEGG: afl:Aflv_1831 stage V sporulation protein E required for spore cortex peptidoglycan synthesis; PFAM: cell cycle protein; SPTR: Stage V sporulation protein E required for spore cortex peptidoglycan synthesis; TIGRFAM: stage V sporulation protein E; cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: stage V sporulation protein E; cell division protein FtsW; Belongs to the SEDS family. | 0.436 |
| Toce_0466 | Toce_1915 | Toce_0466 | Toce_1915 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.932 |
| Toce_0466 | ddl | Toce_0466 | Toce_0210 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.909 |
| Toce_0466 | murD | Toce_0466 | Toce_0950 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.920 |
| Toce_0466 | murE | Toce_0466 | Toce_0947 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.406 |
| Toce_0466 | murF | Toce_0466 | Toce_0948 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.951 |
| Toce_0466 | murG | Toce_0466 | Toce_0952 | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.662 |
| Toce_0946 | Toce_0466 | Toce_0946 | Toce_0466 | COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543:IPR005311:IPR001460:IPR011927; KEGG: hor:Hore_09030 stage V sporulation protein D; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Stage V sporulation protein D; TIGRFAM: stage V sporulation protein D; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: sta [...] | COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011761:IPR011095; KEGG: tpd:Teth39_2176 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. | 0.515 |
| Toce_0946 | Toce_0951 | Toce_0946 | Toce_0951 | COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543:IPR005311:IPR001460:IPR011927; KEGG: hor:Hore_09030 stage V sporulation protein D; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Stage V sporulation protein D; TIGRFAM: stage V sporulation protein D; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: sta [...] | Spore cortex peptidoglycan biosynthesis regulator SpoVE; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR013437:IPR013438; KEGG: afl:Aflv_1831 stage V sporulation protein E required for spore cortex peptidoglycan synthesis; PFAM: cell cycle protein; SPTR: Stage V sporulation protein E required for spore cortex peptidoglycan synthesis; TIGRFAM: stage V sporulation protein E; cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: stage V sporulation protein E; cell division protein FtsW; Belongs to the SEDS family. | 0.983 |
| Toce_0946 | Toce_1915 | Toce_0946 | Toce_1915 | COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543:IPR005311:IPR001460:IPR011927; KEGG: hor:Hore_09030 stage V sporulation protein D; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Stage V sporulation protein D; TIGRFAM: stage V sporulation protein D; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: sta [...] | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.407 |
| Toce_0946 | ddl | Toce_0946 | Toce_0210 | COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543:IPR005311:IPR001460:IPR011927; KEGG: hor:Hore_09030 stage V sporulation protein D; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Stage V sporulation protein D; TIGRFAM: stage V sporulation protein D; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: sta [...] | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.667 |
| Toce_0946 | mraY | Toce_0946 | Toce_0949 | COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543:IPR005311:IPR001460:IPR011927; KEGG: hor:Hore_09030 stage V sporulation protein D; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Stage V sporulation protein D; TIGRFAM: stage V sporulation protein D; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: sta [...] | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.983 |