close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0961RNA polymerase, sigma 29 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (239 aa)    
Predicted Functional Partners:
Toce_0960
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
 
  
 0.942
Toce_0964
Sporulation protein, YlmC/YmxH family; COGs: COG1873 conserved hypothetical protein; InterPro IPR007903:IPR014238; KEGG: csc:Csac_1196 PRC-barrel domain-containing protein; PFAM: PRC-barrel domain protein; SPTR: PRC-barrel domain protein; TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain; TIGRFAM: sporulation protein, YlmC/YmxH family.
 
     0.893
Toce_1300
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.854
Toce_0980
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
 
    0.811
Toce_0100
Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T.
  
    0.806
Toce_2013
InterPro IPR018356:IPR014208; KEGG: hor:Hore_17740 sporulation stage III transcriptional regulator SpoIIID; SPTR: Sporulation stage III transcriptional regulator SpoIIID; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID.
  
    0.805
Toce_2201
Stage II sporulation protein R; InterPro IPR014202; KEGG: tex:Teth514_0606 hypothetical protein; PFAM: Sporulation stage II protein R; SPTR: Stage II sporulation protein R; TIGRFAM: stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R.
 
     0.803
Toce_0962
RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
0.775
Toce_1262
Stage V sporulation protein AE; InterPro IPR014204:IPR005562; KEGG: csc:Csac_0090 SpoVA protein; PFAM: SpoVA protein; SPTR: SpoVA protein; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AE.
  
     0.774
Toce_1263
InterPro IPR010894; KEGG: amt:Amet_2220 stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; SPTR: Stage V sporulation AD family protein; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
  
     0.774
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.