Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
engARibosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (436 aa)    
Predicted Functional Partners:
gpsA
COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR006168:IPR011128:IPR006109:IPR010916; KEGG: cth:Cthe_1022 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: Glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus.
 
  
 0.985
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR008243:IPR000623:IPR011994:IPR003136; KEGG: tit:Thit_1145 cytidylate kinase; PFAM: cytidylate kinase region; Chorismate mutase of the AroH class; shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; chorismate mutase; PFAM: Cytidylate kinase; Chorismate mutase type I; TIGRFAM: cytidylate kinase; monofunctional chorismate mutase, gram positive type, clade 1.
  
 0.981
Toce_0977
Protein of unknown function DUF512; COGs: COG1625 Fe-S oxidoreductase related to NifB/MoaA family; InterPro IPR001478:IPR007549; KEGG: cth:Cthe_1025 hypothetical protein; PFAM: protein of unknown function DUF512; PDZ/DHR/GLGF domain protein; SPTR: Putative uncharacterized protein; PFAM: PDZ domain (Also known as DHR or GLGF); Protein of unknown function (DUF512); TIGRFAM: putative FeS-containing Cyanobacterial-specific oxidoreductase.
 
    0.959
Toce_1071
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
 
 
 0.907
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
 
 0.899
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
    
 
 0.826
rpmG
LSU ribosomal protein L33P; InterPro IPR018264:IPR001705; KEGG: tit:Thit_1990 ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: Ribosomal protein L33; TIGRFAM: ribosomal protein L33; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family.
    
   0.811
rplO
LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
 
 
 0.798
rpmF
COGs: COG0333 Ribosomal protein L32; InterPro IPR002677; KEGG: cce:Ccel_2134 ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: Ribosomal protein L32; TIGRFAM: ribosomal protein L32; PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
   0.795
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 
 0.790
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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