| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0980 | Toce_1300 | Toce_0980 | Toce_1300 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.868 |
| Toce_0980 | Toce_1315 | Toce_0980 | Toce_1315 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | KEGG: tit:Thit_1084 hypothetical protein; SPTR: Stage III sporulation protein AH. | 0.870 |
| Toce_0980 | Toce_1316 | Toce_0980 | Toce_1316 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | KEGG: tit:Thit_1083 stage III sporulation protein AG; SPTR: Stage III sporulation protein AG; TIGRFAM: stage III sporulation protein AG. | 0.859 |
| Toce_0980 | Toce_1319 | Toce_0980 | Toce_1319 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | InterPro IPR014211; KEGG: dae:Dtox_2608 stage III sporulation protein AD; SPTR: Stage III sporulation protein AD; TIGRFAM: stage III sporulation protein AD; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AD. | 0.937 |
| Toce_0980 | Toce_1320 | Toce_0980 | Toce_1320 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage III sporulation protein AC; InterPro IPR009570:IPR005829; KEGG: amt:Amet_2494 stage III sporulation AC family protein; SPTR: Stage III sporulation AC family protein; TIGRFAM: stage III sporulation protein AC; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AC. | 0.863 |
| Toce_0980 | Toce_1322 | Toce_0980 | Toce_1322 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage III sporulation protein AA; COGs: COG3854 conserved hypothetical protein; InterPro IPR014217:IPR003593; KEGG: tpd:Teth39_1088 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase; TIGRFAM: stage III sporulation protein AA; TIGRFAM: stage III sporulation protein AA. | 0.886 |
| Toce_0980 | Toce_2013 | Toce_0980 | Toce_2013 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | InterPro IPR018356:IPR014208; KEGG: hor:Hore_17740 sporulation stage III transcriptional regulator SpoIIID; SPTR: Sporulation stage III transcriptional regulator SpoIIID; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID. | 0.894 |
| Toce_0980 | Toce_2015 | Toce_0980 | Toce_2015 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | COGs: COG2385 Sporulation protein and related protein; InterPro IPR014225:IPR013486:IPR013693; KEGG: tpd:Teth39_2097 SpoIID/LytB domain-containing protein; PFAM: Stage II sporulation D domain protein; SPTR: SpoIID/LytB domain; TIGRFAM: stage II sporulation protein D; SpoIID/LytB domain protein; PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain; stage II sporulation protein D. | 0.893 |
| Toce_0980 | Toce_2201 | Toce_0980 | Toce_2201 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage II sporulation protein R; InterPro IPR014202; KEGG: tex:Teth514_0606 hypothetical protein; PFAM: Sporulation stage II protein R; SPTR: Stage II sporulation protein R; TIGRFAM: stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R. | 0.848 |
| Toce_0980 | spoIIAB | Toce_0980 | Toce_1268 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.854 |
| Toce_1300 | Toce_0980 | Toce_1300 | Toce_0980 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.868 |
| Toce_1300 | Toce_1315 | Toce_1300 | Toce_1315 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | KEGG: tit:Thit_1084 hypothetical protein; SPTR: Stage III sporulation protein AH. | 0.577 |
| Toce_1300 | Toce_1316 | Toce_1300 | Toce_1316 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | KEGG: tit:Thit_1083 stage III sporulation protein AG; SPTR: Stage III sporulation protein AG; TIGRFAM: stage III sporulation protein AG. | 0.772 |
| Toce_1300 | Toce_1319 | Toce_1300 | Toce_1319 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | InterPro IPR014211; KEGG: dae:Dtox_2608 stage III sporulation protein AD; SPTR: Stage III sporulation protein AD; TIGRFAM: stage III sporulation protein AD; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AD. | 0.802 |
| Toce_1300 | Toce_1320 | Toce_1300 | Toce_1320 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AC; InterPro IPR009570:IPR005829; KEGG: amt:Amet_2494 stage III sporulation AC family protein; SPTR: Stage III sporulation AC family protein; TIGRFAM: stage III sporulation protein AC; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AC. | 0.741 |
| Toce_1300 | Toce_1322 | Toce_1300 | Toce_1322 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage III sporulation protein AA; COGs: COG3854 conserved hypothetical protein; InterPro IPR014217:IPR003593; KEGG: tpd:Teth39_1088 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase; TIGRFAM: stage III sporulation protein AA; TIGRFAM: stage III sporulation protein AA. | 0.796 |
| Toce_1300 | Toce_2013 | Toce_1300 | Toce_2013 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | InterPro IPR018356:IPR014208; KEGG: hor:Hore_17740 sporulation stage III transcriptional regulator SpoIIID; SPTR: Sporulation stage III transcriptional regulator SpoIIID; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID. | 0.862 |
| Toce_1300 | Toce_2015 | Toce_1300 | Toce_2015 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | COGs: COG2385 Sporulation protein and related protein; InterPro IPR014225:IPR013486:IPR013693; KEGG: tpd:Teth39_2097 SpoIID/LytB domain-containing protein; PFAM: Stage II sporulation D domain protein; SPTR: SpoIID/LytB domain; TIGRFAM: stage II sporulation protein D; SpoIID/LytB domain protein; PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain; stage II sporulation protein D. | 0.596 |
| Toce_1300 | Toce_2201 | Toce_1300 | Toce_2201 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage II sporulation protein R; InterPro IPR014202; KEGG: tex:Teth514_0606 hypothetical protein; PFAM: Sporulation stage II protein R; SPTR: Stage II sporulation protein R; TIGRFAM: stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R. | 0.823 |
| Toce_1300 | spoIIAB | Toce_1300 | Toce_1268 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.837 |
