Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_0983Replication initiator A domain protein; InterPro IPR010724:IPR001808; KEGG: sau:SAP001 hypothetical protein; PFAM: replication initiator A domain protein; regulatory protein Crp; SPTR: Replication-associated protein RepA; PFAM: Replication initiator protein A (RepA) N-terminus. (281 aa)    
Predicted Functional Partners:
Toce_0984
KEGG: afl:Aflv_0783 hypothetical protein; SPTR: Predicted protein.
       0.773
Toce_0982
Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: nth:Nther_1227 integrase family protein; PFAM: integrase family protein; SPTR: Integrase family protein; manually curated; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; Belongs to the 'phage' integrase family.
     
 0.756
Toce_0985
Hypothetical protein.
       0.746
Toce_0987
IstB domain protein ATP-binding protein; COGs: COG1484 DNA replication protein; InterPro IPR003593:IPR002611; KEGG: cth:Cthe_1996 IstB-like ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; SPTR: IstB-like ATP-binding protein; PFAM: IstB-like ATP binding protein.
  
  
 0.556
Toce_0426
TRAG family protein; COGs: COG3505 Type IV secretory pathway VirD4 protein; InterPro IPR003688; KEGG: tpd:Teth39_0052 TraG family protein; PFAM: TRAG family protein; SPTR: TRAG family protein; PFAM: TraG/TraD family.
 
  
 0.502
Toce_0986
Integrase catalytic region; COGs: COG4584 Transposase and inactivated derivatives; InterPro IPR001584:IPR017894; KEGG: cth:Cthe_1995 hypothetical protein; PFAM: Integrase catalytic region; SPTR: Putative uncharacterized protein; PFAM: Integrase core domain.
       0.467
Toce_0400
Helix-turn-helix domain protein; InterPro IPR001387; KEGG: ckr:CKR_2925 hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Immunity repressor protein; PFAM: Helix-turn-helix.
 
   
 0.437
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
   
 
 0.401
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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