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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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dapLLL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (387 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
  
 0.982
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
    
 0.914
Toce_1760
Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative.
    
 0.914
Toce_1020
YicC domain protein; COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR013551:IPR005229; KEGG: cth:Cthe_1317 hypothetical protein; PFAM: YicC domain protein; domain of unknown function DUF1732; SPTR: Putative uncharacterized protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: conserved hypothetical protein TIGR00255.
       0.751
Toce_1024
Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
   0.725
Toce_1021
Protein of unknown function DUF370; COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: ckr:CKR_1260 hypothetical protein; PFAM: protein of unknown function DUF370; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF370); Belongs to the RemA family.
       0.710
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.699
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
       0.693
Toce_1737
COGs: COG0388 amidohydrolase; InterPro IPR003010:IPR001110; KEGG: gym:GYMC10_2272 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase.
 
  
 0.639
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
  
 0.575
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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