| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_1029 | Toce_1040 | Toce_1029 | Toce_1040 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | 0.647 |
| Toce_1029 | recG | Toce_1029 | Toce_1038 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.548 |
| Toce_1029 | rlmH | Toce_1029 | Toce_2221 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.551 |
| Toce_1029 | rnpA | Toce_1029 | Toce_2284 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.514 |
| Toce_1039 | Toce_1040 | Toce_1039 | Toce_1040 | InterPro IPR001448:IPR018126; KEGG: nth:Nther_1585 small acid-soluble spore protein alpha/beta type; PFAM: small acid-soluble spore protein alpha/beta type; SPTR: Small acid-soluble spore protein alpha/beta type; PFAM: Small, acid-soluble spore proteins, alpha/beta type. | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | 0.475 |
| Toce_1039 | Toce_1042 | Toce_1039 | Toce_1042 | InterPro IPR001448:IPR018126; KEGG: nth:Nther_1585 small acid-soluble spore protein alpha/beta type; PFAM: small acid-soluble spore protein alpha/beta type; SPTR: Small acid-soluble spore protein alpha/beta type; PFAM: Small, acid-soluble spore proteins, alpha/beta type. | KEGG: adg:Adeg_0114 hypothetical protein; SPTR: Archaeal/vacuolar-type H+-ATPase subunit H. | 0.439 |
| Toce_1039 | coaD | Toce_1039 | Toce_1041 | InterPro IPR001448:IPR018126; KEGG: nth:Nther_1585 small acid-soluble spore protein alpha/beta type; PFAM: small acid-soluble spore protein alpha/beta type; SPTR: Small acid-soluble spore protein alpha/beta type; PFAM: Small, acid-soluble spore proteins, alpha/beta type. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.475 |
| Toce_1039 | recG | Toce_1039 | Toce_1038 | InterPro IPR001448:IPR018126; KEGG: nth:Nther_1585 small acid-soluble spore protein alpha/beta type; PFAM: small acid-soluble spore protein alpha/beta type; SPTR: Small acid-soluble spore protein alpha/beta type; PFAM: Small, acid-soluble spore proteins, alpha/beta type. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.591 |
| Toce_1040 | Toce_1029 | Toce_1040 | Toce_1029 | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.647 |
| Toce_1040 | Toce_1039 | Toce_1040 | Toce_1039 | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | InterPro IPR001448:IPR018126; KEGG: nth:Nther_1585 small acid-soluble spore protein alpha/beta type; PFAM: small acid-soluble spore protein alpha/beta type; SPTR: Small acid-soluble spore protein alpha/beta type; PFAM: Small, acid-soluble spore proteins, alpha/beta type. | 0.475 |
| Toce_1040 | Toce_1042 | Toce_1040 | Toce_1042 | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | KEGG: adg:Adeg_0114 hypothetical protein; SPTR: Archaeal/vacuolar-type H+-ATPase subunit H. | 0.848 |
| Toce_1040 | Toce_2283 | Toce_1040 | Toce_2283 | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.754 |
| Toce_1040 | coaD | Toce_1040 | Toce_1041 | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.970 |
| Toce_1040 | engA | Toce_1040 | Toce_0978 | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.509 |
| Toce_1040 | nnrD | Toce_1040 | Toce_1916 | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.540 |
| Toce_1040 | recG | Toce_1040 | Toce_1038 | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.433 |
| Toce_1040 | rlmH | Toce_1040 | Toce_2221 | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.474 |
| Toce_1040 | rnpA | Toce_1040 | Toce_2284 | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.533 |
| Toce_1042 | Toce_1039 | Toce_1042 | Toce_1039 | KEGG: adg:Adeg_0114 hypothetical protein; SPTR: Archaeal/vacuolar-type H+-ATPase subunit H. | InterPro IPR001448:IPR018126; KEGG: nth:Nther_1585 small acid-soluble spore protein alpha/beta type; PFAM: small acid-soluble spore protein alpha/beta type; SPTR: Small acid-soluble spore protein alpha/beta type; PFAM: Small, acid-soluble spore proteins, alpha/beta type. | 0.439 |
| Toce_1042 | Toce_1040 | Toce_1042 | Toce_1040 | KEGG: adg:Adeg_0114 hypothetical protein; SPTR: Archaeal/vacuolar-type H+-ATPase subunit H. | Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family. | 0.848 |