Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)    
Predicted Functional Partners:
Toce_1040
Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: tit:Thit_1294 methyltransferase; PFAM: conserved hypothetical protein; SPTR: Methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family.
 
  
 0.970
coaX
Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
 
  
 0.961
Toce_1024
Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.956
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.955
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
   
 0.798
Toce_1042
KEGG: adg:Adeg_0114 hypothetical protein; SPTR: Archaeal/vacuolar-type H+-ATPase subunit H.
       0.748
Toce_0773
Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR003583:IPR004509:IPR019554:IPR000445; KEGG: mta:Moth_0570 competence protein ComEA helix-hairpin-helix region; PFAM: Soluble ligand binding domain; helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1; SPTR: Competence protein ComEA helix-hairpin-helix region; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; Helix-hairpin-helix motif; TIGRFAM: competence protein ComEA helix-hairpin-helix r [...]
      0.713
Toce_1045
COGs: COG3480 secreted protein containing a PDZ domain; InterPro IPR001478; KEGG: nth:Nther_1352 PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: PDZ/DHR/GLGF domain protein; PFAM: Lon protease (S16) C-terminal proteolytic domain.
 
  
 0.697
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.683
Toce_0042
Cyanophycin synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterProIPR011810:IPR005479:IPR013221:IPR004101:IPR 018109:IPR011761; KEGG: tte:TTE2785 cyanophycin synthetase; PFAM: Mur ligase middle domain protein; Carbamoyl-phosphate synthase L chain ATP-binding; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramyl tripeptide synthase; TIGRFAM: cyanophycin synthetase; PFAM: RimK-like ATP-grasp domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Str [...]
     
 0.661
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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